Senior Scientist - Formulation Science

AstraZeneca; Macclesfield; On-site; GBP 50,000 - 75,000; Full time

Job summary

A leading biopharmaceutical company seeks a Senior Scientist in Formulation Science to innovate and drive projects forward in its Early Product Development and Manufacturing team. The role demands a background in pharmaceutical sciences with expertise in dosage form development and formulation strategies. Join an encouraging environment that values curiosity and collaboration, impacting the future of medicine significantly.

Benefits

Competitive compensation

Excellent Employee Benefits

Robust career development opportunities

Qualifications

• Degree in Pharmaceutical Sciences or a related subject is essential.
• Experience in managing contracted activities at CMOs is beneficial.
• Proven track record in formulating various dosage forms.

Responsibilities

• Plan and perform pre-formulation studies of APIs.
• Drive scientific product design and process for early product development.
• Collaborate with various scientific disciplines and stakeholders.

Skills

Formulation Development

Analytical Collaboration

Scientific Leadership

Education

Master's or PhD in Pharmaceutical Sciences

Job description

Senior Scientist – Formulation Science

Location: Macclesfield, UK

Salary: Competitive+ Excellent Employee Benefits!

Introduction to role:
Are you ready to make a difference in the world of biopharmaceuticals? At AstraZeneca, we are dedicated to discovering and delivering innovative medicines that transform lives. We are seeking a Senior Scientist in Formulation Science to join our Early Product Development and Manufacturing (EPDM) team. In this pivotal role, you will collaborate with experts across various scientific disciplines to drive innovation in drug projects. Are you ready to follow the science and contribute to groundbreaking advancements?

Accountabilities:
As a Senior Scientist, your responsibilities will include:

• Planning and performing pre-formulation studies of APIs based on available preclinical data to develop strategies for clinical dosage forms.

• Crafting robust formulations for early clinical studies that meet patient needs.

• Driving scientific product design, process, and product performance understanding to influence strategies in early product development, with a line of sight to late-stage development.

• Planning and conducting lab-based experimental work to achieve efficient products ready for scale-up to clinical plans in accordance with project timelines.

• Keeping abreast of scientific literature and proactively applying existing and novel approaches to projects.

• Representing the formulation skill area in projects to drive science and innovation.

• Collaborating closely with analytical, manufacturing, biopharmaceutics, and solid-state scientists within EPDM, as well as external stakeholders, to ensure all goals are met.

Essential Skills/Experience:

• Degree (preferably Masters or PhD) in Pharmaceutical Sciences or a related subject.

• Excellent track record of formulating and characterising a variety of dosage forms, including conventional immediate release tablets and capsules, amorphous solid dispersions, nanoparticles, and lipid-based delivery systems.

• Experience in formulation and process development of poorly soluble molecules.

• Experience in managing outsourced activities at Contract Manufacturing Organizations (CMOs).

• Track record as a scientific leader, providing scientific challenge and direction to colleagues.

Desirable Skills/Experience:

• Proven leadership in the scientific subject area of formulation.

• In-depth understanding of how the physicochemical and solid-state properties of the drug, dosage form, and route of administration affect the rate and extent of absorption.

• Track record of authoring high-quality regulatory submissions for IND/IMPD.

• Able to challenge the status quo and implement a culture of continuous improvement.

• Global mindset and ability to work across multiple geographical locations.

Why AstraZeneca?

At AstraZeneca, we stand at the forefront of scientific innovation, passionately merging ground breaking technology with research to redefine the boundaries of drug discovery and personalized healthcare. We cultivate an environment where curiosity and courage propel us to solve the biology of complex diseases without fear of failure, driving bold decisions and ambitious breakthroughs.

Our team thrives in an encouraging atmosphere, equipped with groundbreaking resources that empower professionals to celebrate both their triumphs and setbacks. With us, you will not only impact the future of medicine but also enjoy competitive compensation, benefits, and robust career development opportunities. Join us on this exciting journey to make a meaningful impact in the world.

So, what’s next?

• Are you already imagining yourself joining our team? Great, because we are eager to hear from you.

• Are you ready to bring new insights and fresh thinking to the table in the field of formulation sciences? Fantastic! We have one seat available, and we hope it’s yours.

• Ready to make a significant impact? If you're ready to contribute innovative solutions and drive scientific excellence in drug formulation with one of the world's leading biopharmaceutical companies, apply today!

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

Date Posted

27-May-2025

Closing Date

19-Jun-2025 Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.