Senior Scientist, Discovery Biology (Oncology)

Cancer Research UK

Cambridge

On-site

GBP 42,000 - 51,000

Full time

5 days ago
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Benefits offered by this job

Generous benefits
Career development

Job summary

Cancer Research Horizons (CRH) at Cancer Research UK is seeking a Senior Scientist in bioscience for a permanent, lab-based role at Babraham Research Campus, Cambridge. You will contribute to defining critical path biology for small and large molecules, and work with Target Validation and Translational Biology to address portfolio challenges.

The successful candidate will apply extensive cancer biology expertise to biomarker discovery, disease mechanism interrogation, and drug discovery

Qualifications

  • PhD in cancer biology or related field with industry experience.
  • Strong background in biomarker discovery and pharmacology concepts.
  • Experience applying PD biomarkers to drug discovery programs.

Responsibilities

  • Design, perform and interpret gene perturbation studies in cancer models.
  • Conduct phenotypic analyses including proliferation and apoptosis assays.
  • Elucidate drug-target engagement and downstream pathway effects.
  • Identify biomarkers to support translation from preclinical to clinical.
  • Review literature to identify clinical positioning opportunities.

Skills

Cancer biology
Biomarker discovery
Drug discovery
PD biomarkers
Experimental design

Education

PhD in Cancer Biology
BSc/MSc with industry experience

Tools

Proteomics
Simple Western
RT-qPCR
Flow Cytometry
Immunofluorescence

Job description

Cancer Research Horizons (CRH) at Cancer Research UK is seeking a Senior Scientist in bioscience for a permanent, lab-based role at Babraham Research Campus, Cambridge. You will contribute to defining critical path biology for small and large molecules, and work with Target Validation and Translational Biology to address portfolio challenges.

The successful candidate will apply extensive cancer biology expertise to biomarker discovery, disease mechanism interrogation, and drug discovery

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