Senior Scientist 2 - Vectorology

TN United Kingdom; Cambridge; On-site; GBP 50,000 - 70,000; Full time

Job summary

A leading company in bioproduction seeks a Senior Scientist 2 specializing in vectorology. The role involves developing next-generation expression vectors for protein-based and viral vector therapeutics. Candidates should possess a strong background in molecular and cell biology, with hands-on experience in vector design and optimization. This position offers the opportunity to lead innovative research projects and mentor junior scientists in a collaborative environment.

Qualifications

• Minimum 5 years of experience in virology, molecular biology, biochemistry, or genetics.
• Proven track record in designing and optimizing expression vectors.

Responsibilities

• Lead independent research projects from design to execution.
• Engineer novel expression vector systems for therapeutics.
• Mentor junior scientists and maintain lab documentation.

Skills

Molecular Biology

Cell Biology

Team Collaboration

Communication

Scientific Curiosity

Education

M.Sc. in Life Sciences

Ph.D.

Tools

PCR

qPCR

ddPCR

Gibson Assembly

Golden Gate Assembly

Job description

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Senior Scientist 2 - Vectorology, Cambridge

Client:

Location:

Cambridge, United Kingdom

Job Category:

Other

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EU work permit required:

Yes

Job Reference:

955f67af3841

Job Views:

4

Posted:

12.05.2025

Expiry Date:

26.06.2025

Job Description:

Revvity's R&D Bioproduction department pioneers advanced expression platforms that power the manufacturing of next-generation biotherapeutics. Our portfolio includes specialized mammalian host cell lines and our innovative transposon-based expression system, designed to rapidly identify high-expressing recombinant protein clones. Through our gene editing expertise, we deliver custom cell line engineering services that precisely tailor bioproduction cell lines to meet our clients' specific manufacturing requirements for both protein-based and viral vector therapeutics.

Job summary

As a Senior Scientist 2 in our Bioproduction R&D team, you will serve as our vectorology subject matter expert, driving the development of next-generation expression vectors to strengthen Revvity's bioproduction capabilities. Your work will shape innovative vector systems designed to improve production efficiency for both protein-based therapeutics and viral vector products.

This lab-based role requires hands-on expertise and deep theoretical knowledge in vectorology, molecular biology, and cell biology for biotherapeutic production.

Key responsibilities:

1. Lead independent research projects from design through execution, analysis, and troubleshooting with meticulous attention to detail.
2. Engineer novel expression vector systems optimized for both protein-based therapeutics and viral vector production.
3. Develop innovative solutions for challenging vector design problems, including difficult-to-express proteins and complex viral assemblies.
4. Mentor junior scientists through training, troubleshooting, and data review.
5. Foster collaborative relationships within the team and across Revvity departments.
6. Maintain comprehensive laboratory documentation and develop standard operating procedures.
7. Present clear, concise data at both internal and external meetings.
8. M.Sc. in life sciences with Ph.D. plus minimum 5 years of demonstrated experience in a relevant scientific discipline (virology, molecular biology, biochemistry, or genetics).
9. Proven track record designing and optimizing expression vectors for both protein therapeutics and viral vector production systems.
10. Advanced molecular biology skills, including expertise in diverse cloning methods (Gibson assembly, Golden Gate assembly), PCR, qPCR, and ddPCR.
11. Experience applying Design of Experiment (DoE) methodologies to experimental design.
12. Hands-on experience with transposon-based expression systems.
13. Extensive background in recombinant protein expression methods and in-depth knowledge of mammalian Cell Line Development.
14. Exceptional team collaboration skills with strong communication abilities and meticulous attention to detail.
15. Demonstrated scientific curiosity with a proactive approach to knowledge development.