Senior Research HPC Engineer

MRC Laboratory of Medical Sciences; City Of London; On-site; GBP 58,000 - 68,000; Full time

Benefits offered by this job

Pension scheme

Holiday entitlement

Family leave

Discounts

Employee assistance

Health and wellbeing

Cycle to work

Job summary

The MRC Laboratory of Medical Sciences in London invites applications for a Senior Research HPC Engineer to design, manage, and develop LMS's next‑generation HPC infrastructure. You will work across Linux, SLURM, and cluster automation to improve performance, reliability, and accessibility for biomedical researchers.

The role combines hands‑on systems engineering with collaboration with scientists and other engineers to translate research needs into robust, scalable computational solutions

Qualifications

• Extensive experience across HPC and systems technologies including Linux system administration, software installation and lifecycle management, job scheduling and configuration management.
• Experience with cluster automation and performance monitoring and optimisation.
• Ability to translate research needs into robust, practical, sustainable technological solutions.

Responsibilities

• Design, manage and develop the next generation of LMS HPC infrastructure.
• Identify opportunities to improve performance, reliability, scalability and accessibility.
• Collaborate with LMS IT colleagues, scientists, researchers and other engineers to deliver robust solutions.

Skills

Linux system administration

Job scheduling

Cluster automation

Performance monitoring

Software installation

Lifecycle management

Hardware maintenance

Tools

SLURM scheduler

Bash scripting

Job description

Senior Research HPC Engineer

MRC Laboratory of Medical Sciences

MRC Band 3-S1: £57,623 - £61,622 plus London Allowance £5,560 per annum

Higher salary of £61,622 - £67,693 plus London Allowance of £5,560 per annum will be available for candidates with significant relevant experience

Permanent contract

Hammersmith Hospital Campus, London, UK

About us

The MRC Laboratory of Medical Sciences (LMS) is a biomedical research institute where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. The LMS is home to more than 400 research staff and postgraduate students and is based at Hammersmith Hospital, with close links to Imperial College London and Imperial College Healthcare NHS Trust. LMS IT operates its own dedicated HPC environment, which is extensively used by multidisciplinary research groups and Institute facilities. The LMS IT department currently manages a SLURM-based cluster comprising CPU, high-memory (HMEM), and GPU nodes, supporting a diverse range of computational research.

About the role

As the Institute’s computational requirements continue to grow, the postholder will take a proactive role in designing, managing, and developing the next generation of LMS HPC infrastructure. This will include identifying opportunities to improve performance, reliability, scalability, and accessibility, as well as exploring interactive computing solutions that can enable a broader range of researchers to make effective use of HPC resources.

The successful candidate will bring substantial knowledge and practical experience across a broad range of HPC and systems technologies, including Linux system administration, software installation and lifecycle management, job scheduling and configuration management, cluster automation, performance monitoring and optimisation, and working with LMS IT colleagues for general hardware maintenance.

About You

We are seeking an experience and motivated Senior Research HPC Engineer to join the MRC Laboratory of Medical Sciences (LMS) and play a key role in expanding the Institute’s scientific computing capabilities. This is an exciting opportunity for an HPC professional who wants to combine hands‑on engineering with direct scientific impact, supporting cutting‑edge research in computational biology.

This role is particularly well suited to someone who enjoys hands‑on systems engineering, working with and developing scientific and computational workflows, exploring emerging technologies, collaborating closely with scientists, researchers and other engineers. The successful candidate will be expected to understand research needs and translate them into robust, practical, and sustainable technological solutions that enable biomedical scientific discovery.

What we offer

As well as the exciting opportunities this role presents, we also offer defined benefit pension scheme and excellent holiday entitlement (30 days plus 2.5 privilege days & 8 bank holidays), family friendly policies (6 months full pay maternity & adoption leave), a range of shopping/travel discounts, access to our Employee Assistant Programme Scheme, Health and Wellbeing Support and a salary sacrifice cycle to work scheme. Please follow this link to find out more - Benefits

Closing date: 18 October 2026

Final appointment will be subject to pre-employment screening

Applications may be reviewed by both LMS and Imperial staff