Senior Quantitative Pharmacologist

TN United Kingdom; Cambridge; On-site; GBP 60,000 - 100,000; Full time

Job description

Job Title: Senior Quantitative Pharmacologist, Cambridge

Client:

Location:

Cambridge, United Kingdom

Job Category:

Other

EU work permit required:

Yes

Job Reference:

068e8858d9c0

Job Views:

7

Posted:

24.04.2025

Expiry Date:

08.06.2025

Job Description:

We are seeking a Senior Quantitative Pharmacologist to contribute significantly to multiple programs. The role involves executing PK, PD, and other quantitative analyses that support drug development. The candidate will collaborate across teams to evaluate, design, and apply scientific techniques to analyze in-vivo and in-vitro pharmacokinetic and pharmacodynamic studies, and prepare study reports and regulatory documents.

Typical Responsibilities:

1. Plan, design, and analyze PMx studies with collaboration and supervision.
2. Perform quantitative PK or PK/PD analyses such as NCA, compartmental modeling, PopPK, translational modeling, disease modeling, and E-R analyses.
3. Collaborate with research and programming teams to prepare technical reports supporting regulatory submissions.
4. Support regulatory interactions by preparing materials and additional analyses as needed.

Ideal Candidate:

- Excellent interpersonal and communication skills, able to work independently.

- Familiarity with regulatory and research guidelines (e.g., ICH, GxP).

- Ability to make decisions independently and proactively.

Minimum Qualifications:

- PhD with 3+ years of relevant experience in quantitative pharmacology.

- Strong understanding of quantitative methods including non-compartmental analysis, compartmental modeling, translational pharmacology, Exposure-Response analysis, Nonlinear Mixed Effects modeling, and disease modeling/QSP.

- Experience with advanced statistical methods applicable to clinical trials such as survival analysis, covariate analysis, handling missing data, logistic regression, and Bayesian approaches.