Senior Project Manager - Technical Operations

Milestone Technologies, Inc.; Greater London; On-site; GBP 90,000 - 120,000; Full time

Job summary

Milestone Technologies, Inc. is seeking an experienced Global Senior Project Manager – Technical Operations to lead complex, cross-functional pharma projects across Europe, the US, and Asia.

You will drive projects from initiation to handover in a global PMO, coordinating with internal sites, CDMOs, vendors, and stakeholders. The role manages multiple concurrent projects, including technical transfers, packaging changes, process improvements, and strategic operations initiatives, within a

Qualifications

• Minimum 8 years of project management in pharma/biopharma.
• Experience managing multiple concurrent projects in a global setting.
• Strong understanding of pharma development, manufacturing and operations.
• Experience budgeting, forecasts and financial reporting.
• Strong stakeholder management, negotiation and influencing skills.
• Knowledge of GxP and regulatory frameworks (FDA/EMA).
• PMP certification preferred; other leadership experience considered.

Responsibilities

• Lead initiation and governance for cross-functional projects in global pharma.
• Align objectives with business strategy and priorities.
• Develop charters with milestones, risks, schedules and RAICIs.
• Build and lead global cross-functional project teams.
• Manage lifecycle, stage-gate approvals, scope and budgets.
• Oversee schedules, budgets, risks, and deliverables.
• Facilitate governance reviews and executive status updates.
• Ensure on-time, on-budget delivery per objectives.
• Identify and mitigate risks and issues proactively.
• Serve as main contact for sponsors, leadership, vendors and partners.
• Ensure compliance with GxP, FDA/EMA and company quality.
• Support regulatory submission activities as needed; maintain data in ePM systems.

Skills

8+ years project management experience

Global/ cross-functional leadership

Budgeting and financial reporting

Stakeholder management

GxP regulatory awareness (FDA/EMA)

Risk management and governance

PMP certification preferred

Technical Operations / Pharma

MS Project / portfolio tools

Education

Scientific, engineering, pharmaceutical sciences background

Tools

MS Project

Job description

We are seeking an experienced Global Senior Project Manager – Technical Operations to lead complex, cross-functional projects supporting commercial pharmaceutical products across Europe, the United States, and Asia. This role sits within a global Technical Operations PMO and is responsible for driving projects from initiation through operational handover while partnering with internal manufacturing sites, contract manufacturing organizations (CDMOs), vendors, and global stakeholders.

The successful candidate will independently manage multiple concurrent projects, typically overseeing four projects at a time, ranging from technical transfers and packaging changes to manufacturing process improvements and strategic operational initiatives.

12 month project contract

Key Responsibilities

• Lead project initiation activities, aligning project objectives with business strategy and organizational priorities.
• Partner with project sponsors and functional leaders to establish governance, scope, timelines, budgets, resources, and success criteria.
• Develop comprehensive project charters, including milestones, deliverables, risk assessments, schedules, and RACI models.
• Build and lead global cross-functional project teams.
• Manage projects through all lifecycle stages and stage-gate approvals.
• Oversee project schedules, scope, budgets, risks, and deliverables.
• Facilitate project meetings, governance reviews, and executive status updates.
• Ensure projects are delivered on time, within budget, and according to agreed objective
• Identify, assess, and mitigate project risks and issues proactively.
• Serve as the primary point of contact for project sponsors, leadership teams, project members, vendors, and external partners.
• Ensure projects comply with applicable GxP, FDA, EMA, and company quality requirements.
• Support project-related regulatory submission activities where required.Maintain accurate project information within project portfolio management systems and reporting tools.

Required Qualifications

• Minimum 8 years of project management experience within the pharmaceutical or biopharmaceutical industry.
• Proven experience managing multiple concurrent projects in a complex global environment.
• Strong understanding of pharmaceutical development, manufacturing, and Technical Operations environments.
• Experience managing project budgets, forecasts, and financial reporting.
• Strong stakeholder management, communication, negotiation, and influencing skills.
• Working knowlExcellent problem-solving, organizational, and decision-making skills.edge of GxP requirements and regulatory frameworks, including FDA and EMA regulations.
• PMP certification preferred; equivalent project/program leadership experience will also be considered.
• Scientific, engineering, pharmaceutical sciences, or related technical background.
• Proficiency with Microsoft Project or other enterprise portfolio management tools.

The ideal candidate is a seasoned pharmaceutical project management professional who thrives in a global matrix environment, can independently lead complex Technical Operations projects, and is comfortable coordinating diverse stakeholders across internal teams, manufacturing sites, CMOs, and external partners. They bring strong leadership, governance, financial management, and risk management capabilities while ensuring successful project delivery in a regulated environment.