Senior Production Chemist — GMP-Driven Polymers & Scale-Up

Sava

Greater London

On-site

GBP 55,000 - 75,000

Full time

6 days ago
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Job summary

SAVA is redefining health tech with cutting-edge biosensing materials. We are seeking a Senior Production Chemist to turn validated chemistry into GMP-compliant production, owning synthesis, QC, and batch documentation for our polymer components.

Ideal candidates will have 4+ years in chemical production under GMP, strong multi-step synthesis skills, and experience with QC methods like NMR, HPLC, KF. Join us to build the production function and mentor others in a high-impact health technology

Qualifications

  • Degree in chemistry or related discipline.
  • 4+ years’ experience in a chemical production or manufacturing environment.
  • Hands-on experience working under GMP.
  • Strong multi-step synthesis and purification at 50–500 g scale.
  • Experience with QC techniques such as NMR, HPLC, elemental analysis and KF.
  • Strong GMP documentation experience, including batch records, deviations, CAPA and change control.
  • Meticulous attention to detail and a quality-first mindset.

Responsibilities

  • Carry out GMP synthesis of sensor polymers using validated MPIs.
  • Plan production to meet manufacturing demand.
  • Support planned scale increases (up to ~200 g) in partnership with R&D.
  • Manage raw materials, reagents and supplier CoAs.
  • Perform QC testing using validated methods (e.g. NMR, HPLC, KF, elemental analysis).
  • Critically review QC methods and specifications, and help bring them in line with GMP.
  • Investigate OOS results and deviations, and drive CAPA.
  • Maintain safe working practices, including risk assessments for scaled reactions.

Skills

Attention to detail
Quality-first mindset
Production planning

Education

Degree in chemistry or related discipline

Tools

NMR
HPLC
KF (Karl Fischer)
Elemental analysis

Job description

SAVA is redefining health tech with cutting-edge biosensing materials. We are seeking a Senior Production Chemist to turn validated chemistry into GMP-compliant production, owning synthesis, QC, and batch documentation for our polymer components.

Ideal candidates will have 4+ years in chemical production under GMP, strong multi-step synthesis skills, and experience with QC methods like NMR, HPLC, KF. Join us to build the production function and mentor others in a high-impact health technology

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