Senior Principal DS Scientist (Drug Substance)

Proclinical Staffing; Wrexham; On-site; GBP 60,000 - 100,000; Full time

Job summary

An established industry player is seeking a Senior Principal Scientist to spearhead strategic projects in biomanufacturing processes. This pivotal role focuses on developing innovative solutions for API and drug substance processing, ensuring high standards of quality and efficiency. The successful candidate will lead the Purification Chromatography Community of Practice and drive continuous improvement initiatives while collaborating with multidisciplinary teams. If you are passionate about leading scientific innovation and aligning technical programs with business objectives, this opportunity is perfect for you.

Qualifications

• Expertise in biomanufacturing processes, including upstream and downstream strategies.
• Proven leadership in managing multidisciplinary scientific teams.

Responsibilities

• Lead and manage biomanufacturing processes, ensuring quality and efficiency.
• Mentor and develop a team of scientists for superior performance.

Skills

Biomanufacturing processes

Fermentation

Purification

Chromatography

Filtration

Leadership

CMC development

Regulatory requirements

Innovation

Collaboration

Job description

Senior Principal DS Scientist - Permanent - Wrexham, UK

Proclinical is seeking a Senior Principal Scientist to lead strategic projects in biomanufacturing processes, focusing on API/Drug substance processing. This role involves developing innovative solutions for upstream and downstream strategies, ensuring high standards of quality and efficiency. You will serve as the scientific leader for API/Drug substance manufacturing and lead the Purification Chromatography Community of Practice.

The Senior Principal DS (Drug Substance) Scientist will:

• Expertise in MS&T bioprocesses, including fermentation, purification, chromatography, and filtration.
• Proven leadership skills in managing multidisciplinary scientific teams.
• In-depth knowledge of CMC development and global regulatory requirements.
• Experience in driving innovation and continuous improvement initiatives.
• Strong collaboration and communication skills with internal and external stakeholders.
• Ability to align technical programs with business objectives and manage budgets and timelines.

Skills & Requirements:

• Lead and manage biomanufacturing processes, including upstream and downstream strategies.
• Mentor and develop a team of scientists, structuring their work for superior performance.
• Oversee advanced projects, ensuring timelines, budgets, and quality standards are met.
• Design and implement analytical and process characterization strategies for API/DS processes.
• Foster innovation by encouraging new methodologies and technologies.
• Ensure compliance with regulatory guidelines and prepare teams for successful inspections.
• Collaborate with internal stakeholders and external vendors to ensure project success.

If you are having difficulty in applying or if you have any questions, please contact Ruhee Saleh at [e-mail].

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.