Senior/Principal Bioinformatician

Hlx Life Sciences; Cambridge; Hybrid; GBP 55,000 - 75,000; Full time

Job summary

A leading company in biotechnology is seeking a Senior or Principal Bioinformatician to drive innovative analyses that support drug discovery initiatives. The role requires collaboration across teams and expertise in bioinformatics, particularly in cancer biology and programming. This hybrid position involves three days on-site work per week.

Qualifications

• PhD in bioinformatics or related field required.
• Experience in using bioinformatics tools for drug development.
• Advanced programming skills in Python or similar.

Responsibilities

• Lead bioinformatic analyses to support drug discovery.
• Collaborate across teams to deliver high-value analyses.
• Maintain internal bioinformatic tools.

Skills

Bioinformatics

Cancer Biology

Python

Statistical Testing

Education

PhD in Bioinformatics

Tools

Git

Job description

Direct message the job poster from Hlx Life Sciences

We are looking for a driven and experienced Senior or Principal Bioinformatician to lead the design and execution of bioinformatic analyses that support a variety of drug discovery initiatives. The role involves leveraging both public and proprietary large-scale patient, genomic, and functional datasets to guide and inform the company’s drug discovery priorities.

Key Responsibilities

• Provide innovative solutions to complex biological problems to gain new insights into multiple aspects of drug discovery.
• Collaborate with colleagues across the company to translate business needs into high value analysis in a timely fashion
• Work as a team to exploit and expand the data science infrastructure to meet business needs in a rapidly evolving environment.
• Expand and maintain internal bioinformatic tools.
• Work to achieve scientific deliverables and milestones at agreed quality and timescales. Identify and mitigate risks as they emerge.
• Establish appropriate communication with line manager, project team members and other stakeholders to ensure they are kept informed of workloads, issues, progress, results, innovation and developments.
• Actively demonstrate best practice and behaviours to create a positive, productive and inclusive working environment.
• Communicate analytical products and outputs to stakeholders.
• Seek input and feedback from internal and external stakeholders about their requirements and prioritize your workload.
• Interact with the Leadership team, project teams and external collaborators to aid in the delivery of projects.
• Contribute to the general duties of the company and pass on skills and knowledge to other team members.

Skills Required

[E = Essential D/E = Essential at Principal level D = Desirable]

• A PhD in bioinformatics, pharmacology, molecular biology or related scientific discipline and/or experience in bioinformatics gained in academia or industry (E)
• Knowledge of cancer biology, cancer genomics, or cancer therapeutics (E)
• Experience of using bioinformatics tools to guide drug development in areas such as biomarker identification, patient selection, mechanisms of action and resistance (E)
• A track record of developing analytical solutions to complex biological problems (E)
• Advanced knowledge of programming in Python or similar (E)
• Experience in the integration, analysis and functional interpretation of omics experiments/datasets (transcriptomics, proteomics, CRISPR) (E)
• Experience using statistical testing, including hypothesis testing and power analysis (E)

Desirable for Senior Role, Essential for Principal Role:

• Experience in the analysis of large-scale genomic and functional genomic datasets through the use of automated workflows (D/E)
• Experience in analysis of clinical data analysis (D/E)
• Experience with cloud computing and software containerization (D)
• Knowledge of current software development methodologies e.g. Scrum/Agile, CI/CD, Concurrent Version Systems (e.g. Git) (D)
• Previous experience developing, deploying and maintaining software tools (D/E)
• Previous experience of developing, deploying and/or maintaining web user interfaces and/or REST APIs (D)

This is a hybrid role that requires 3 days on-site per week

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Science

• Industries

  Biotechnology Research and Pharmaceutical Manufacturing

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