Senior PK/PD Statistical Programmer (R + NONMEM)

IQVIA Inc; Reading; Hybrid; GBP 70,000 - 90,000; Full time

Job summary

IQVIA Inc. is seeking an experienced PK/PD Statistical Programmer in Reading to deliver NONMEM‑ready PK/PD datasets using SDTM/ADaM standards and advanced R skills.

You will create high‑quality datasets for pre‑ and post‑lock data, perform QC, and support regulatory deliverables while collaborating with Data Management, Biostatistics, and other teams to ensure data integrity and operational excellence.

Qualifications

• Bachelor’s or Master’s degree in a health, science, IT, mathematics, or related field.
• Minimum 6 years of industry experience in clinical data analysis, statistical programming, or pharmacometrics support.
• Expert‑level proficiency in R for data processing, dataset creation, and QC automation.
• Hands‑on experience creating NONMEM datasets, including complex data structures for PK/PD analyses.
• Strong understanding of SDTM, ADaM, and controlled terminology.
• Applied knowledge of PK/PD principles and clinical trial concepts.
• High attention to detail with strong analytical, documentation, and communication skills.
• Ability to work independently and collaboratively across global, cross‑functional teams.

Responsibilities

• Program, validate, and deliver NONMEM‑ready PK/PD datasets based on SDTM/ADaM standards using advanced R programming skills.
• Create high‑quality PK/PD datasets for both pre‑lock and post‑lock clinical data.
• Independently execute programming tasks of medium to high complexity with excellent accuracy and timeliness.
• Critically review data, identify inconsistencies or gaps, and propose solutions to improve dataset quality and programming efficiency.
• Perform QC of NONMEM datasets, including those produced by external partners.
• Support preparation of deliverables for regulatory submissions following internal Pharmacometrics guidelines.
• Conduct QC of customized R packages used for pharmacometrics workflows; enhance or build automated test suites where needed.
• Liaise with cross‑functional teams including Data Management, Biostatistics, Statistical Programming, and Bioanalytical groups to resolve data issues and ensure alignment.
• Adhere to relevant SOPs, working instructions, and regulatory standards; maintain inspection readiness.
• Contribute as a technical driver in the development and improvement of new PM standardization initiatives related to dataset creation and QC.

Skills

R programming

PK/PD datasets

NONMEM dataset creation

SDTM/ADaM

QC automation

Cross-functional collaboration

Education

Bachelor’s or Master’s degree in health/science/IT/math

Tools

R

Job description

IQVIA Inc. is seeking an experienced PK/PD Statistical Programmer in Reading to deliver NONMEM‑ready PK/PD datasets using SDTM/ADaM standards and advanced R skills.

You will create high‑quality datasets for pre‑ and post‑lock data, perform QC, and support regulatory deliverables while collaborating with Data Management, Biostatistics, and other teams to ensure data integrity and operational excellence.