Senior PK/PD Programmer (R & NONMEM)

IQVIA; Reading; On-site; GBP 75,000 - 110,000; Full time

Job summary

IQVIA in Reading, UK seeks an experienced PK/PD Statistical Programmer to support pharmacometrics by producing high-quality NONMEM-ready PK/PD datasets using SDTM/ADaM standards.

The role requires expert-level R programming, deep PK/PD knowledge, and 6+ years in clinical data analysis or pharmacometrics, with a focus on data integrity and regulatory-ready deliverables.

You’ll liaise with Data Management, Biostatistics, and external partners in a fast-moving, regulated environment.

Qualifications

• Bachelor’s or Master’s degree in health, science, IT, mathematics, or related field.
• Minimum 6 years of industry experience in clinical data analysis or pharmacometrics.
• Expert-level proficiency in R for data processing and QC automation.
• Hands-on experience creating NONMEM datasets for PK/PD analyses.
• Strong knowledge of SDTM, ADaM, and controlled terminology.

Responsibilities

• Program, validate, and deliver NONMEM-ready PK/PD datasets based on SDTM/ADaM standards using advanced R programming skills.
• Create high-quality PK/PD datasets for both pre-lock and post-lock clinical data. Independently execute programming tasks of medium to high complexity with excellent accuracy.
• Critically review data, identify inconsistencies or gaps, and propose solutions to improve dataset quality and programming efficiency.
• Perform QC of NONMEM datasets, including those produced by external partners; support regulatory deliverables.
• Conduct QC of customized R packages used for pharmacometrics workflows; enhance or build automated test suites where needed.
• Liaise with Data Management, Biostatistics, Statistical Programming, and Bioanalytical groups to resolve data issues and ensure alignment.
• Adhere to SOPs and regulatory standards; maintain inspection readiness.
• Contribute as a technical driver in new PM standardization initiatives related to dataset creation and QC.

Skills

R programming

PK/PD datasets

NONMEM dataset creation

Education

Bachelor’s or Master’s degree in health, science, IT, mathematics, or related field

Job description

IQVIA in Reading, UK seeks an experienced PK/PD Statistical Programmer to support pharmacometrics by producing high-quality NONMEM-ready PK/PD datasets using SDTM/ADaM standards.

The role requires expert-level R programming, deep PK/PD knowledge, and 6+ years in clinical data analysis or pharmacometrics, with a focus on data integrity and regulatory-ready deliverables.

You’ll liaise with Data Management, Biostatistics, and external partners in a fast-moving, regulated environment.