Senior Manager, Global Clinical Science - Cardiovascular

Bristol-Myers Squibb; Uxbridge; On-site; GBP 85,000 - 120,000; Full time

Job summary

Bristol Myers Squibb in the UK is seeking a Senior Manager, Global Clinical Science – Cardiovascular to lead diligence and development efforts for cardiovascular assets. You will collaborate with senior BD and clinical teams to shape trial design, valuation, and strategy across early to late development stages.

The role requires strong knowledge of GCP/ICH, study design, statistics, and medical writing, with the ability to coordinate cross-functional inputs from Biostatistics, Regulatory,

Qualifications

• Intermediate knowledge of GCP/ICH, drug development process, study design, statistics, and clinical operations.
• Intermediate knowledge to support program-specific data review and trend identification and deal-specific competitive trend identification.
• Intermediate medical writing skills and medical terminology applied to diligence memos/deal narratives.
• Intermediate planning/project management skills to develop short-range plans across clinical development program and deal timelines.

Responsibilities

• Collaborate with external partners and contribute to diligence discussions with scientific/clinical contacts.
• Provide regular updates to manager and leadership as requested.
• Conduct literature reviews to inform asset valuation and trial design benchmarking.
• Contribute to developing the clinical development plan spanning early to late development and present to governance committee.
• Lead review of clinical trial design elements to inform feasibility and valuation.
• Partner with senior BD team members to build trial design and feasibility benchmarking materials.
• Contribute clinical input to diligence packages in coordination with senior BD leads.
• Collaborate cross-functionally with Biostatistics, Regulatory, Commercial, and Medical Affairs.
• Maintain working knowledge of key cardiovascular therapeutic areas relevant to portfolio and pipeline.
• May provide guidance to associate or junior clinical scientists on assigned initiatives.

Skills

GCP/ICH knowledge

Drug development process

Study design

Statistics

Clinical operations

Medical writing

Project management

MS Word/Excel/PowerPoint

Data review tools

Education

Life Sciences degree (MD/PhD/PharmD/MS/RN)

MBA or business/finance coursework (plus)

Job description

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

Position Responsibilities

• Collaborate and liaise with external partners (e.g., key opinion leaders), and contribute directly to diligence-related conversations with target company scientific/clinical contacts, working alongside senior BD leads
• Seek out and enact best practices with instruction
• Provide regular and timely updates to manager/management as requested
• Conduct literature review, including competitive landscape research, to inform asset valuation and trial design benchmarking on prospective deals in partnership with senior BD team members
• Contribute to developing the clinical development plan spanning early to late development and present these to governance committee and development team meetings as required
• Lead review of clinical trial design elements (endpoints, statistical assumptions, enrollment criteria) of target assets and precedent/competitor trials, in partnership with senior BD team members, to inform feasibility and valuation assumptions
• Partner with senior BD team members to build trial design and feasibility benchmarking materials (sample size, enrollment assumptions, country selection) for asset valuation and deal feasibility assessments
• Contribute clinical input to diligence packages in coordination with senior BD leads
• Collaborate cross-functionally with Biostatistics, Regulatory, Commercial, and Medical Affairs to inform clinical development and diligence assessments
• Maintain working knowledge of key cardiovascular therapeutic areas (e.g., lipid management, coronary artery disease, stroke, and heart failure) relevant to portfolio and pipeline assessment
• May provide guidance to associate or junior clinical scientists on assigned initiatives

Degree Requirements

• Degree in Life Sciences (MD, PhD, Pharm D, MS, RN or other scientific field preferred). Five to seven years industry experience preferred. MBA or business/finance coursework a plus but not required.

Experience Requirements

• Intermediate knowledge of GCP/ICH, drug development process, study design, statistics, clinical operations
• Intermediate knowledge and skills to support program-specific data review and trend identification, as well as deal‑specific competitive trend identification
• Intermediate medical writing skills and medical terminology, applied to diligence memos/deal narratives
• Intermediate planning/project management skills (develop short range plans that are realistic and effective across both clinical development program and deal timelines)

Key Competency Requirements

• Intermediate knowledge of disease area and current clinical landscape
• Intermediate knowledge of the establishment and operation of data monitoring committees, dose review teams, and independent response adjudication committees
• Basic knowledge of deal structuring norms (upfront/milestone/royalty structures) and asset valuation frameworks (NPV/eNPV, PTRS); training provided, not required at entry
• Intermediate to advanced critical thinking and problem‑solving skills
• Adaptable / flexible (willing and able to adjust to multiple demands and shifting priorities across clinical and BD workstreams; ability to meet day‑to‑day challenges with confidence and professionalism)
• Intermediate skills in Microsoft Word/Excel/PowerPoint and data review tools (e.g., report generating tools)

How We Work

Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site‑essential, site‑by‑design, field‑based and remote‑by‑design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

R1604164 : Senior Manager, Global Clinical Science - Cardiovascular