Senior Manager, Clinical Sciences – Genomics Medicine

Regeneron Pharmaceuticals; Cambridge; On-site; GBP 113,000 - 184,000; Full time

Job summary

Regeneron Pharmaceuticals seeks a Senior Manager to join our Clinical Sciences team within Regeneron Genetics Medicine, supporting early development in a fast-paced, collaborative environment. You will contribute to clinical strategy and study execution from discovery through Proof of Concept, translating genetic insights into potential new treatments.

Collaborate with your supervisor, Clinical Trial Managers, and cross-functional study teams to ensure compliant, high-quality trial execution and

Qualifications

• Bachelor’s degree and 8+ years of clinical research/development experience.
• Preferred: PhD, PharmD, or Master’s degree in a biomedical subject.
• Training as a scientist in the pharmaceutical or biotechnology sector, or in an academic or clinical setting.
• Effective verbal and written communication and presentation skills.
• Ability to work productively in a fast-paced, collaborative environment.
• Demonstrated or potential critical thinking skills and sound decision-making.
• Preferred: Experience in early-phase development, including First-In-Human and Proof of Concept studies.

Responsibilities

• Represent the clinical genetics medicine function on study teams, contributing medical and scientific expertise to compliant, high-quality trial execution
• Contribute to Clinical Study Concepts, protocols, and amendments, supported by literature research on indication selection, rationale, and endpoints
• Draft clinical sections of regulatory and clinical documents, including briefing books, IND/IMPD submissions, investigator’s brochures, consent forms, and study reports
• Review key study documents such as medical monitoring plans, statistical analysis plans, and data management materials
• Partner with Clinical Trial Managers to provide day-to-day clinical input and train study team and CRO personnel on clinical aspects of the trial
• Support medical monitoring, investigator queries, safety narratives, and trend analysis of safety and efficacy data
• Organize steering committees, advisory boards, data safety monitoring boards, and consultations with global subject matter experts
• Identify program, trial, and data risks and implement mitigation strategies, while ensuring compliance with FDA, EMEA, ICH, and GCP guidelines

Skills

Clinical research

Regulatory familiarity

Communication skills

Team collaboration

Critical thinking

Early-phase experience

Education

Bachelor’s degree

PhD/PharmD/Master’s in biomedical subject

Job description

Regeneron Pharmaceuticals seeks a Senior Manager to join our Clinical Sciences team within Regeneron Genetics Medicine, supporting early development in a fast-paced, collaborative environment. You will contribute to clinical strategy and study execution from discovery through Proof of Concept, translating genetic insights into potential new treatments.

Collaborate with your supervisor, Clinical Trial Managers, and cross-functional study teams to ensure compliant, high-quality trial execution and