Senior Manager, Accounts Payable

Autolus Therapeutics; Greater London; Hybrid; GBP 75,000 - 110,000; Full time

Job summary

Autolus is seeking a Senior Manager, Accounts Payable Operations to lead an established AP team in a fast-paced biotech environment. You will own end-to-end AP processes, drive controls, and partner with Procurement, Finance and business units to optimise P2P performance.

Based in London with hybrid working, the role requires strong leadership, extensive AP knowledge, and a track record of implementing process improvements and system enhancements within a high-volume finance operation.

Qualifications

• Significant AP/Procure-to-Pay experience.
• Experience leading AP teams in high-volume environments.
• Strong knowledge of invoice processing, payment controls and month-end close.
• Experience with ERP and fintech systems.

Responsibilities

• Lead centralized AP team ensuring timely vendor payments and quality service.
• Oversee full AP lifecycle: receipt, validation, coding, approvals, payments, reconciliations.
• Collaborate with Procurement Ops to onboard suppliers and optimise processes.
• Develop and monitor AP performance metrics and drive process improvements.

Skills

Operational leadership

Team management

Attention to detail

Stakeholder communication

Internal controls

Process improvement

Biotech knowledge

Education

AAT Level 4

Degree or higher-level qualification

Tools

ERP systems

Fintech tools

Job description

Work with us

Our team are passionate in the pursuit of excellence and in pushing the boundaries of cancer therapy and Autoimmune disease to deliver life-changing treatments to patients.

Whilst working at Autolus you will enjoy a flexible, diverse and dynamic working environment which actively promotes creativity, leadership and teamwork - together we are ONE Autolus.

Job Description:

Job Title: Senior Manager, Accounts Payable Operations

Reports to Head of Procurement Operations

Department: Procurement Operations

Hours:Full Time

Location: Mediaworks, White City London - Hybrid Working

About Autolus

Autolus is a biopharmaceutical company, advancing innovative therapies at both clinical and commercial stages of development, focused on next-generation, programmed T cell therapies for the treatment of cancer. Using a broad suite of proprietary and modular T cell programming technologies, the company is engineering precisely targeted, controlled, and highly active T cell therapies designed to better recognize cancer cells, break down their defence mechanisms, and eliminate these cells. Autolus has a pipeline of product candidates in development for the treatment of haematological malignancies, solid tumours, and autoimmune diseases.

Why Autolus

Our team is passionate in the pursuit of excellence and in pushing the boundaries of cancer therapy and autoimmune diseases to deliver life-changing treatments to patients. Whilst working at Autolus you will enjoy a flexible, diverse, and dynamic working environment which actively promotes creativity, leadership and teamwork. In addition to this Autolus is proud to offer a competitive salary, performance related bonus as well as a comprehensive benefits package.

Our Promise

Autolus is developing complex, breakthrough therapies for a globally diverse market and equally recognises that diversity amongst our people is critical to our mission. As we draw on our differences, what we’ve experienced, and how we work, we celebrate diversity and are committed to creating an inclusive environment for all employees.

Role Summary

Managing an established team of 3 you will oversee the end-to-end Accounts Payable operations, ensuring accurate invoice processing, timely supplier payments, robust controls, effective vendor management, and continuous improvement across processes, systems, and service delivery.

You will own the financial and operational controls, process documentation, governance and reporting for the end-to-end Purchase-to-Pay process. Implement best-in-class AP applications and processes, while continually identifying opportunities to improve system and process efficiency and supporting the delivery of change.

This is a hands-on role in a fast-changing environment, requiring adaptability and original thinking. You will work closely with the wider Finance team, Procurement Operations, and other departments across the business, building strong and effective working relationships.

The manager will be a member of the Procurement Operations Management Team reporting to the Head of Procurement Operations and part of a high performing team accountable for the delivery of an efficient and controlled Procure to Pay capability.

Key Responsibilities

• Responsible for the centralised Accounts Payable team ensuring effective process, efficiency, accuracy and providing a good service to the company with timely vendor payments.
• Responsible for ownership and operational administration of the Company’s expense management / P card platform, including day-to-day monitoring of employee expense activity, policy compliance, user support, workflow management and reporting, Act as the primary Finance contact for all expense-related matters and ensure accurate, timely, and compliant expense processing across the organisation.
• Oversee the full accounts payable lifecycle, including invoice receipt, validation, coding, approvals, payment runs, supplier statement reconciliations, and exception management.
• Collaborate with Procurement Operations to oversee various processes such as supplier onboarding into ERP system.
• Maintain robust controls over payment processing, segregation of duties, duplicate-payment prevention, fraud risk, and audit readiness.
• Lead month, quarter and year-end AP close activities, including accrual support, ageing reviews, reconciliations, and reporting.
• Partner with Procurement, Finance and business teams to improve procure-to-pay performance and compliance.
• Identify opportunities to simplify, standardise, automate, and improve AP processes and controls to drive improvement and efficiencies across the business.
• Develop, Deliver and Monitor AP performance metrics, such as invoice processing cycle times, payment accuracy, overdue invoices, exception rates, supplier query volumes, and days payable outstanding
• Other ad-hoc duties including support to project teams in development and implementation of infrastructural projects and implementation of processes

Leadership and People Management

• Lead, coach, and develop the Accounts Payable operations team, setting clear objectives and performance expectations.
• Allocate workload, manage capacity, and ensure effective cover for critical activities.
• Build a customer-focus set expectations and adopt continuous-improvement culture.
• Support recruitment, onboarding, training, and capability development within the AP team.

Systems, Automation, and Process Improvement

• Own or support AP system configuration, workflow optimisation, automation adoption, and data quality improvements.
• Work with IT, Finance Systems, and Procurement Systems teams to resolve system issues and improve user experience.
• Use AP reporting and analytics to identify process bottlenecks, control gaps, supplier issues, and improvement opportunities.
• Support transformation initiatives such as e-invoicing, purchase order compliance, automated approvals, supplier portals, and invoice scanning capture tools.

Demonstrated skills and competencies

E – Essential

P – Preferred

• Strong operational leadership and team management capability. E
• Excellent attention to detail, analytical thinking, and problem-solving skills. E
• Clear communication skills with the ability to engage suppliers, senior stakeholders, and cross-functional teams. E
• Good understanding of internal controls, audit requirements, risk management, and payment governance. E
• Ability to manage competing priorities in a fast-paced, deadline-driven environment. E
• Continuous improvement mindset with experience improving processes, service levels, and controls. E
• Hands on, resilient and flexible to thrive in a fast-paced environment - E
• Biotech, clinical background – P
• Proven business partnering skills - E

Experience

• Significant experience in Accounts Payable, Procure-to-Pay, Finance Operations, or Shared Services environments. E
• Proven experience leading AP teams and managing high-volume transactional finance operations. E
• Strong knowledge of invoice processing, payment controls, supplier reconciliations, month-end close, and financial compliance requirement. E
• Experience with ERP and Fintech systems and tools. E
• Knowledge of working in shared service centre environment a plus. P

Qualifications

• AAT Level 4 qualified (or studying towards), or equivalent qualification or experience. E
• Degree or higher-level qualification. P

Autolus Core Competencies

Focus on Results: Works to meet business goals set by management and leaders

Builds Trust and Relationships: Ensures trust with internal and external partners by delivering on commitments

Resilience: Has the capacity to recover quickly from difficulties; toughness

Communicates and Collaborates: Builds partnerships and works collaboratively with others to meet objectives

Autolus is committed to the protection of the personal information that we collect & process and we are fully compliant with General Data Protection Regulations (GDPR)

Autolus is committed to providing an inclusive and fair workplace for all. We are an equal opportunity employer and do not discriminate on the basis of race, colour, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic. We also provide reasonable accommodationswhereappropriate.

Autolus is committed to the protection of the personal information that we collect & process and we are fully compliant with General Data Protection Regulations (GDPR).

Autolus is committed to providing an inclusive and fair workplace for all. We are an equal opportunity employer and do not discriminate on the basis of race, colour, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic. We also provide reasonable accommodations throughout the recruitment process.

Autolus’ success is driven by equality and inclusion; we believe all voices are of equal value and must be heard. Whilst operating with focus and integrity, we are committed to improving diversity and inclusion within our business and our industry.