Senior Machine Learning Engineer

Isomorphic Labs; City Of London; On-site; GBP 70,000 - 90,000; Full time

Job summary

A leading biotechnology company in London seeks a Senior Machine Learning Engineer to join their Applied ML team. This role involves building cutting-edge ML models for drug design in collaboration with world-class researchers. Candidates should have strong programming skills, experience with ML frameworks, and a background in software engineering. This position aims to drive innovation and has the potential to transform drug discovery.

Qualifications

• Strong experience with developing large-scale machine learning models.
• Extensive programming experience using any mainstream programming languages.
• Experience with the full ML research and development lifecycle.

Responsibilities

• Partner with research teams to design, develop, train, and evaluate ML models.
• Build a scalable ML drug design research environment.
• Maximise model performance for production use.

Skills

Developing large-scale machine learning models

Strong Python experience

Experience with JAX, PyTorch or TensorFlow

Software design / architecture skills

Understanding of ML theory and applications

Education

Bachelor’s degree in Computer Science or equivalent

Job description

About Iso

Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.

Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.

We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.

Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.

Senior Machine Learning Engineer

Your impact

Join our expanding Applied ML team and apply your expertise to cutting-edge ML models, specifically working with Bio models. This role offers the unique opportunity to collaborate closely with world-class researchers to drive innovation.

Working in a highly creative, iterative environment, you will be partnering with leading engineers, scientists and ML researchers to build the critical platform driving that transformation. This is a newly created role and you will need to use your previous experience and show initiative in order to fully carve out your contribution.

What you will do

• Partner with the ML Research, Drug Design, and Data Engineering teams to design, develop, train, and evaluate a variety of cutting edge ML models at unprecedented scale.
• Build a world-class ML drug design research environment with scalable software and libraries.
• Develop tools and libraries to enable large-scale machine learning experiments across thousands of accelerators.
• Maximise model performance, scalability, and robustness for production use within our computational platform.
• Create novel instrumental drug discovery tools in partnership with domain experts. Take end-to-end ownership from rapid prototyping to production-quality code.
• Iterate collaboratively with scientists and domain experts to deeply understand feature requirements and user feedback.

Skills and qualifications

• Strong experience with developing large-scale machine learning models.
• Extensive programming experience using any mainstream programming languages, including strong Python experience.
• Experience with modern ML frameworks including at least one of JAX, PyTorch or TensorFlow.
• Experience with the full ML research and development lifecycle.
• Experience partnering with research and product teams to prototype and ideally productionise ML models.
• Strong software engineering experience with software design / architecture skills.
• Strong understanding of ML theory and applications.
• Strong understanding of data structures and algorithms.
• Either a Bachelor’s degree in Computer Science, a related technical field, or equivalent practical experience.

Nice to have

• Interest in chemistry and biology.
• Experience working with biomedical data.
• Knowledge of the pharmaceutical industry, ideally with a focus on drug discovery.

Culture and values

We are guided by our shared values. It\'s not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.

Thoughtful Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.

Brave Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.

Determined Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.

Together Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.