Senior Laboratory Research Scientist – Santos Lab

TN United Kingdom; London; On-site; GBP 45,000 - 75,000; Full time

Job summary

An innovative research lab is seeking a Senior Research Scientist to explore the dynamics of cell division and differentiation. This role offers the chance to lead exciting projects using advanced stem cell models, contributing to groundbreaking discoveries in cell biology. The ideal candidate will thrive in a collaborative environment, benefiting from mentorship and training while fostering a positive lab atmosphere. Join a diverse team dedicated to understanding the complexities of cellular behavior, where your expertise will play a crucial role in advancing scientific knowledge and innovation.

Qualifications

• PhD in a relevant Life Sciences field is essential.
• Extensive experience in Molecular Biology and cell culture techniques.

Responsibilities

• Lead research projects under the supervision of the Group Leader.
• Contribute to scientific manuscript preparation and collaborative projects.

Skills

Molecular Biology

Cell Culture Techniques

Imaging/Microscopy

Organizational Skills

Communication Skills

Analytical Mindset

Education

PhD in Life Sciences

Job description

Job Description:

Senior Research Scientist – Santos Lab

Reports to: Silvia Santos, Group Leader

Summary

The Quantitative Stem Cell Biology lab, headed by Dr. Silvia Santos, is seeking a Senior Laboratory Research Scientist (SLRS). The successful candidate will investigate the spatio-temporal control of cell division and cell cycle remodelling during cellular differentiation using 2D and 3D stem cell-based models of human gastrulation. The postholder will lead a research project and contribute to collaborative projects within the lab. They will benefit from excellent mentorship and training in a vibrant, collegial scientific community at the Francis Crick Institute.

The research group

The Quantitative Stem Cell Biology lab, established in 2018, focuses on understanding cell decision-making, regulation of cell fate specification, cell cycle remodeling during differentiation, and the interplay between metabolism, cell cycle, and cell fate. The lab specializes in single-cell analysis and live cell imaging, using models such as mouse and human embryonic stem cells, organoids, and mouse embryos.

The team is multidisciplinary and diverse, comprising PhD students, postdoctoral fellows, and a principal research scientist. The lab promotes independent thinking and provides excellent training and mentorship.

For more information, visit the lab's website.

Key responsibilities

1. Lead specific research projects under the supervision of the Group Leader.
2. Participate in collaborative projects.
3. Attend and contribute to group meetings and seminars.
4. Maintain accurate records of all work.
5. Train junior colleagues when appropriate.
6. Contribute to scientific manuscript preparation.
7. Participate in the lab's hESC feeding rota.
8. Foster a positive and motivating lab environment.

Key experience and competencies

The candidate should embody the Crick values: bold, imaginative, open, dynamic, and collegial, and have:

Essential qualifications and experience:

• PhD in a relevant Life Sciences field.
• Extensive experience in Molecular Biology.
• Experience with cell culture techniques.
• Experience with imaging/microscopy.
• Motivation to understand cell division in development and disease contexts.
• Excellent organizational skills and meticulous record-keeping.
• Strong communication and interpersonal skills.
• Ability to work independently and contribute to publications.

Desirable qualifications and experience:

• Experience with stem cell culture, especially hESCs/iPSCs.
• Experience with image analysis.
• Analytical mindset.
• Track record of publishing scientific papers.

The position will close once an appropriate candidate is found. We encourage early applications.