Senior Compute Platform Engineer

Biopharma Careers; Greater London; On-site; GBP 90,000 - 130,000; Full time

Job summary

GSK is seeking a Sr. Compute Platform Engineer to design, build, and operate a hybrid on-prem/cloud compute platform. You will drive scalable batch computing, CI/CD deployments, and robust tooling for science teams, ensuring performance and reliability across distributed systems.

You’ll mentor junior engineers, contribute to code quality and documentation, and collaborate with DevOps and data platforms to optimize workflows and observability.

Qualifications

• Bachelor's degree in data engineering, Computer Science, Software Engineering or related discipline.
• Experience with Python and cloud technologies.
• Experience with High Performance Compute (HPC).
• Demonstrated excellence with agile software development environments using tools like Jira and Confluence.

Responsibilities

• Designs, builds, and operates tools, services, workflows delivering high value to business problems.
• Develops a hybrid on-prem/cloud compute platform for interactive and scalable batch computing.
• Implements CI/CD driven deployments and container/image builds.
• Consults science users on application scalability and performance in distributed computing environments.
• Optimizes design and execution of complex solutions in large-scale systems.
• Produces well-engineered software with automated tests and operational planning.
• Ensures consistent platform abstractions for logging and lineage.
• Participates in code reviews and improves team standards.
• Guides improvements to CI/CD practices and related workflows.

Skills

Python

Cloud

HPC

Git/GitHub

CI/CD

Docker

Kubernetes

Software engineering

Agile

Education

Bachelor's degree in data engineering, Computer Science, Software Engineering or related discipline

Tools

Docker

Kubernetes

Helm

Argo Workflow

Airflow

Nextflow

Snakemake

CMake

MPI

Gloo

Job description

At GSK, we want to supercharge our data capability to better understand our patients and accelerate our ability to discover vaccines and medicines. The Onyx Research Data Platform organization represents a major investment by GSK R&D and Digital & Tech, designed to deliver a step-change in our ability to leverage data, knowledge, and prediction to find new medicines.

We are a full-stack shop consisting of product and portfolio leadership, data engineering, infrastructure and DevOps, data / metadata / knowledge platforms, and AI/ML and analysis platforms, all geared toward:

• Building a next-generation, metadata- and automation-driven data experience for GSK’s scientists, engineers, and decision-makers, increasing productivity and reducing time spent on “data mechanics”
• Providing best-in-class AI/ML and data analysis environments to accelerate our predictive capabilities and attract top-tier talent
• Aggressively engineering our data at scale, as one unified asset, to unlock the value of our unique collection of data and predictions in real-time

Our Compute Platform Engineering team is building a first-in-class platform of toolchains and workflows that accelerate application development, scale up computational experiments, and integrate all computation with project metadata, logs, experiment configuration and performance tracking over abstractions that encompass Cloud and High-Performance Computing. This metadata-forward, CI/CD-driven platform represents and enables the entire application and analysis lifecycle including interactive development and explorations (notebooks), large-scale batch processing, observability and production application deployments.

A Sr. Compute Platform Engineer is a leading technical contributor who can consistently take a poorly defined business or technical problem, work it to a well-defined problem / specification, and execute on it at a high level. They have a strong focus on metrics, both for the impact of their work and for its inner workings / operations. They are a model for the team on best practice for software development in general (and their specialization in particular), including code quality, documentation, DevOps practices, and testing, and consistently mentor junior members of the team. They ensure robustness of our services and serve as an escalation point in the operation of existing services, pipelines, and workflows.

A Sr. Compute Platform Engineer should be deeply familiar with the tools of their specialization and of their customers and engaged with the open-source community surrounding them – potentially, even to the level of contributing pull requests.

Key Responsibilities:

• Designs, builds, and operates tools, services, workflows, etc that deliver high value through the solution to key business problems,
• Responsible for development of key components of a hybrid on-prem/cloud compute platform for both interactive and scalable batch computing and establishing of processes and workflows to transition existing HPC users and teams to this platform,
• Responsible for code-driven environment, applications, and container/image builds as well as CI/CD driven application deployments.,
• Consult science users on application scalability to PBs of data by having a deep understanding of software engineering, algorithms, and underlying hardware infrastructure and their impact on performance.,
• Confidently optimizes design and execution of complex solutions within large-scale distributed computing environments,
• Produces well-engineered software, including appropriate automated test suites, technical documentation, and operational strategy,
• Ensure consistent application of platform abstractions to ensure quality and consistency with respect to logging and lineage,
• Fully versed in coding best practices and ways of working, and participates in code reviews and partnering to improve the team’s standards,
• Adhere to QMS framework and CI/CD best practices and helps to guide improvements to them that improve ways of working,
• Provide leadership to team members to help others get the job done right

Why You?

Basic Qualifications:

• Bachelor's degree in data engineering, Computer Science, Software Engineering or related discipline
• Experience with Python
• Experience with Cloud
• Experience with High Performance Compute (HPC)

Preferred Qualifications:

• Deep knowledge and use of at least one common programming language: e.g., Python, C++, Java, including toolchains for documentation, testing, and operations / observability
• Deep expertise in modern software development tools / ways of working (e.g. git/GitHub, devops tools, metrics / monitoring, …)
• Deep cloud expertise (e.g., AWS, Google Cloud, Azure), including infrastructure-as-code tools and scalable compute technologies, such as Google Batch and Vertex
• Experience with CI/CD implementations using git and a common CI/CD stack (e.g., Azure DevOps, CloudBuild, Jenkins, CircleCI, GitLab)
• Deep expertise with Docker, Kubernetes, and the larger CNCF ecosystem including experience with application deployment tools such as Helm
• Experience with low level application builds tools (make, CMake) as well as automated build systems such as spack or easybuild
• Application experience of CI/CD implementations using git and a common CI/CD stack (e.g., Jenkins, CircleCI, GitLab, Azure DevOps)
• Experience in workflow orchestration with tools such as Argo Workflow, Airflow, and scientific workflow tools such as Nextflow, Snakemake, VisTrails, or Cromwell
• Experience with application performance tuning and optimization, including in parallel and distributed computing paradigms and communication libraries such as MPI, OpenMP, Gloo, including deep understanding of the underlying systems (hardware, networks, storage) and their impact on application performance.
• Demonstrated excellence with agile software development environments using tools like Jira and Confluence
• Deep familiarity with the tools, techniques, optimizations in high-performance applications space, including engagement with the opensource community (and potentially making contributions to such tools)

#GSKOnyx

#LI-GSK

Skills Algorithms, Data Assessment, Decision Making, Exploratory Data Analysis (EDA), Feature Engineering, Hypothesis Testing, Mathematics Modeling, Predictive Modeling, Probabilistic Modeling, Statistical Analysis, Statistical Analysis Techniques

Why GSK?

Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

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