Senior Computational Chemist: AI-Driven Drug Discovery (Hybrid)

Sygnature Discovery; Macclesfield; Hybrid; GBP 40,000 - 60,000; Full time

Benefits offered by this job

25 days annual leave

Private Medical Insurance

Life Insurance

Employee Assistance Programme

Enhanced Family Friendly Policies

Sygnature Group Pension Scheme

1 paid volunteer day per year

Job summary

Sygnature Discovery is looking for experienced Computational Chemists to join our group at Alderley Park. In this hybrid role, you will work on exciting drug discovery projects with leading global biotech and pharma companies.

The ideal candidate will have a PhD in Computational Chemistry, with expertise in structure-based design and ligand-based design, as well as experience in virtual screening and protein modelling. We offer a dynamic environment and a comprehensive benefits package.

Qualifications

• 2 to 3 years of experience in Computational Chemistry.
• Experience in structure-based design and ligand binding optimisation.
• Familiarity with SAR analysis and ADME/Tox properties.

Responsibilities

• Work on integrated drug discovery projects with biotech and pharma companies.
• Apply generative AI and ML techniques in drug design.
• Contribute to proposal writing for business development.

Skills

Computational Chemistry

Presentation skills

Ligand-based design

Virtual screening

Protein modelling

Data pipelining

Python scripting

Education

PhD in Computational Chemistry or Chemistry

Tools

Scientific software

Job description

Sygnature Discovery is looking for experienced Computational Chemists to join our group at Alderley Park. In this hybrid role, you will work on exciting drug discovery projects with leading global biotech and pharma companies.

The ideal candidate will have a PhD in Computational Chemistry, with expertise in structure-based design and ligand-based design, as well as experience in virtual screening and protein modelling. We offer a dynamic environment and a comprehensive benefits package.