Senior Clinical Trial Manager

Biotech Partners

Boston

Hybrid

GBP 74,477 - 96,820

Full time

14 days+

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Job summary

An innovative biotech company is seeking a Senior Clinical Trial Manager to lead global clinical trials for a novel therapeutic candidate. This pivotal role demands strong leadership and operational excellence to navigate the complexities of clinical research within a collaborative environment. Candidates should possess extensive experience in managing clinical trials and a strategic mindset to align with company goals.

Qualifications

8+ years of clinical trial management experience.
Expertise in global trial conduct and regulatory requirements.
Strong collaboration and operational results delivery skills.

Responsibilities

Lead operations for global clinical trials with an emphasis on start-up activities.
Manage ongoing monitoring processes and site selections.
Oversee financial aspects, including vendor budgets and investigator grants.

Skills

Leadership

Project Management

Risk Assessment

Vendor Management

Problem Solving

Education

Bachelor’s degree in life science or health-related discipline

Job description

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Location: Boston, Massachusetts (Hybrid – 2–3 days/week in-office)

A growing, innovative biotech company is seeking a Senior Clinical Trial Manager to lead the planning, execution, and oversight of a First-in-Human (FIH) clinical trial for a novel therapeutic candidate. This role provides the opportunity to work at the forefront of clinical research, managing global end-to-end trial activities and ensuring alignment with clinical and regulatory milestones.

The successful candidate will bring a strategic mindset, operational excellence, and strong leadership skills to help advance the company’s clinical development goals in a dynamic and collaborative environment.

Key Responsibilities

Lead day-to-day operations for global clinical trials across major functional areas, with an initial emphasis on start-up activities.
Manage site feasibility, site selection, site initiation, and ongoing monitoring processes.
Serve as the primary point of contact for all clinical trial stakeholders including internal teams, CROs, and other external vendors.
Oversee financial aspects of the trial including vendor budgets, investigator grants, invoice reviews, and forecasting.
Organize and lead clinical trial trainings such as investigator meetings and site initiation visits.
Contribute to the development and finalization of key trial documents including study protocols and clinical study reports.
Coordinate IRB/IEC and regulatory submissions to support global trial compliance and timelines.
Champion proactive communication, accountability, and problem-solving across cross-functional teams.
Conduct risk assessments and mitigation planning throughout trial execution.
Support regulatory inspections and quality audits as a Subject Matter Expert (SME).
Provide mentorship and leadership to junior Clinical Operations staff as needed.

Qualifications

Bachelor’s degree (or equivalent experience), preferably in a life science or health-related discipline.
Minimum of 8 years of experience in clinical trial management within pharmaceutical, biotech, or CRO settings.
Proven expertise in global trial conduct, vendor oversight, and stakeholder management.
Strong knowledge of clinical research methodologies, Good Clinical Practice (GCP), ICH guidelines, and global regulatory requirements.
Effective at managing timelines, budgets, and collaborative vendor relationships.
Demonstrated leadership in fostering cross-functional collaboration and delivering operational results.
Willingness to travel up to 20% as needed.

Seniority level