Senior/ Clinical Research Fellow ( Christie- Peter Mac)

NHS; Manchester; On-site; GBP 49,000 - 71,000; Full time

Job summary

A leading cancer center in Manchester offers a unique 2-year Clinical Fellowship focused on early phase clinical trials. The role involves managing trial patients, contributing to research, and the opportunity for a fully funded postgraduate MD degree. Candidates must have completed foundation training and hold GMC registration.

Benefits

Fully funded postgraduate MD degree

Support for continuing professional development

Qualifications

• GMC registration required.
• Evidence of productive ethical research relevant to oncology.
• Experience in general oncology and internal medicine.

Responsibilities

• Manage trial patients through consultations and follow-ups.
• Participate in phase I clinical trials as a sub-investigator.
• Attend safety review committee meetings and liaise with stakeholders.

Skills

Clinical Leadership Skills

Excellent Communication Skills

Flexibility

Teamwork

Education

Completion of foundation training

CCT in Medical or Clinical Oncology

MRCP or equivalent

Job description

Job summary

This is a unique opportunity to undertake a 2-year clinical fellowship based between two world leading Phase I units, year 1 spent at The Christie NHS Foundation Trust in Manchester, UK, and year 2 moving to The Peter MacCallum Cancer Centre in Melbourne, Australia. We are seeking an ambitious, innovative individual with an interest in early phase clinical trials and research.

With consultant oversight, you will be responsible for seeing new referrals, follow-ups & managing the patient throughout all aspects of their trial experience. There is also opportunity to undertake a postgraduate MD degree (fully funded and co-supervised by colleagues at The Christie and Peter MacCullum) via The University of Manchester.

The position is suitable for individuals post-FY2 (or equivalent) through to having completed their specialist training in Oncology, and who wish to gain further experience in experimental medicine and Phase I trials, including first-in-human trials, clinical pharmacology trials & translational research. Our teams deliver trials in all major solid tumour types.

Salary will be on The Christie and Peter MacCullum scales in line with appropriate clinical experience. Candidates are encouraged to discuss the renumeration package ahead of application. We anticipate the fellowship commencing in Manchester between Summer 2025 and February 2026, with some flexibility.

Main duties of the job

The portfolio includes a diverse range of clinical research trials. Following training, you will be expected to participate in these studies as a sub-investigator. These may include phase I trials of small molecule inhibitors, next-generation chemotherapy trials, combination / multi-modality phase I trials, advanced therapy trials, molecular characterisation / translational studies, radiotherapy trials

You will be involved in managing all aspects of trial patients (both in outpatient & in-patients setting), across a diverse range of solid tumours, through new patient consultation, consent & screening patients & reviewing patients at follow-up appointments.

You will be expected to attend safety review committee meetings to discuss trial patients. This will involve close liaison with the Principal Investigators. In addition, you will interface with external stakeholders such as CROs & pharmaceutical sponsors.

You will be expected to attend monthly molecular tumour board meetings to discuss trial patients and to agree opportunities for patients to enrol in early phase trials.

You will be expected to undertake the administrative duties associated with the care of our patients. You will be given opportunities and will be encouraged to be involved in the development & planning of new studies.

There is potential to present your research work and you will be expected to be involved in writing papers and reviews. You will also be required to undergo an annual appraisal.

About us

The Christie is one of Europe's leading cancer centres, treating over 60,000 patients a year. We are based in Manchester and serve a population of 3.2 million across Greater Manchester & Cheshire, but as a national specialist around 15% patients are referred to us from other parts of the country. We provide radiotherapy through one of the largest radiotherapy departments in the world; chemotherapy on site and through 14 other hospitals; highly specialist surgery for complex and rare cancer; and a wide range of support and diagnostic services. We are also an international leader in research, with world first breakthroughs for over 100 years. We run one of the largest early clinical trial units in Europe with over 300 trials every year. Cancer research in Manchester, most of which is undertaken on the Christie site, has been officially ranked the best in the UK.

Details Date posted

23 May 2025

Pay scheme

Hospital medical and dental staff

Grade

Doctor - other

Salary

£49,909 to £70,425 a year per annum

Contract

Fixed term

Duration

12 months

Working pattern

Full-time

Reference number

413-MD-C2025-24418-LP

Job locations

Research & Development - A00181

Manchester

M20 4BX

Job description Job responsibilities

DUTIES AND RESPONSIBILITIES

The medical establishment based at The Christie provides 5 Consultant Medical Oncologists, and 3+ Senior/Clinical Fellows within the ECM team. The medical establishment based at Peter MacCullum is integrated into the Department of Medical Oncology; with 7-8 of these Consultant Medical Oncologists acting as Principal Investigators in the Early Drug Development Program, along with 4 Early Drug Development Fellows integrated with the team.

Continuing Professional Development

The Trust supports the requirements for continuing professional development (CPD) as laid down by the GMC and surgical colleges and is committed to providing time and financial support for these activities.

Role Planning

ROLE: The successful candidate will be recruited as a Clinical Fellow/Senior Clinical Fellow in the Experimental Cancer Medicine Team. The candidate will then undertake the second part of the fellowship at The Peter MacCullum Cancer Centre in Melbourne. The Melbourne element of the fellowship will include a full job description relevant and relative to the Peter MacCullum Cancer Centre based role, and is structured in a similar manner to the role at The Christie.

RESEARCH: A diverse range of clinical research trials are in progress and, following training, the post holder will be expected to participate in these studies as a sub-investigator. These include phase I trials of small molecule inhibitors, next-generation chemotherapy trials, combination / multi-modality phase I trials, molecular characterisation / translational studies.

The post holder will be involved in managing all aspects of trial patients, through new patient consultation, consent and screening patients and reviewing patients at follow-up appointments. Primarily, patients are seen in the outpatient setting but with some inpatient cover. The appointee is required to attend 4-5 trial outpatient clinics per week (see indicative timetable).

The post holder will be expected to attend Safety Review Committee meetings (usually remotely) to discuss trial patients. This will involve close liaison with the trial Principal Investigators, referring consultant body across the Trust and other members of the team. In addition, the post-holder will interface with external stakeholders such as CROs and pharmaceutical sponsors.

The post-holder will be expected to attend monthly molecular tumour board meetings to discuss trial patients and to agree opportunities for patients to enroll in early phase trials.

PROTOCOLS: The post holder will be expected to undertake the administrative duties associated with the care of their patients. The appointee will be encouraged to harness opportunities to be involved in the development and planning of new studies.

Professional Development: The Clinical Fellow will maintain a level of continuing professional development consistent with the recommendations of the Royal College of Physicians. Appropriate arrangements for study leave will be made in conjunction with colleagues. There is the potential to present research work and the post holder will be expected to be involved in audit, writing papers and reviews. The post holder will also be required to undergo an annual appraisal.

Teaching Commitment:

a) Undergraduate

The appointee will be required to contribute to the undergraduate teaching of medical students on oncology topics.

b) Postgraduate

There is a busy postgraduate teaching programme and staff are often requested to lecture on relevant topics. The post holder will be expected to contribute actively to the education of junior doctors, specialty trainees and fellows on the team.

The post holder will also be expected to help in the training of nursing and multi-disciplinary staff in both in-patient and outpatient departments.

Clinical Governance: The post holder will be expected to participate in all relevant aspects of clinical governance, including maintaining up to date protocols, guidelines and clinical audit, under the supervision of the other consultants in the team.

Audit: The appointee will play a full role in clinical audit as a member of The Christie Medical Staff Committee. The appointee will develop, supervise and deliver team audit projects.

This is a 10 session non-training post funded through The Christie NHS Foundation Trust for an initial period of 1 year, to be followed by an additional year of the fellowship at The Peter MacCullum Cancer Centre in Melbourne with their Phase I/Early Drug Development team.

Provisional Sessional Timetable for Senior Clinical Fellow in Experimental Medicine

___________________________________________________________

Proposed Sessional Activities

Outpatient Clinics 5.0

Research Administration 2.0

Teaching 1.0

Trial Teleconferences 0.5

Team Meeting 0.5

Audit/CPD 1.0

10

A Sessional Activity is 4 hours

On call Commitments

This role does not require participation in the Trusts on-call rota.

PERSON SPECIFICATION

Essential for the post

Desirable for the post

METHOD OF ASSESSMENT

1. ATTAINMENTS

Educational

Completion of foundation training or acute care

common Stem programme (or

equivalent)

CCT in Medical or Clinical Oncology or equivalent.

Good Clinical Practice.

Advanced Life Support.

Higher degree in cancer research

AF

CE

Qualifications

MRCP or equivalent

Professional Qualifications

GMC registration

CE

Research / Publications

Evidence of productive ethical research relevant to oncology

Recent publications in peer-reviewed journals.

Conference presentations

AF

I

R

2. TRAINING

Experience in general

oncology and internal

medicine

Research/Trials experience

Experience in managing critically ill patients

AF

I

R

3. EXPERIENCE

Job Specific

Evidence of clinical leadership skills

Phase I trials experience

AF

I

R

Management / Audit

Experience of developing, supervising and delivering audit projects

AF

I

R

4. TEACHING

Experience in teaching undergraduates

Experience in teaching postgraduates.Teaching Qualification

AF

I

R

5. PERSONAL SKILLS

Evidence of clinical skills.

Excellent written and oral communication skills, flexibility, commitment and team work with colleagues and staff in the department; ability to work under pressure; capacity for staff motivation

Demonstration of excellent communication skills

AF

I

R

CE

6. CIRCUMSTANCES

Domicile

Occupational Health ClearanceEnhanced CRB Clearance

CE

Abbreviations for Methods of Assessment:

AF Application Form

I Interview

R References

CE Certification Evidence

Job description Job responsibilities

DUTIES AND RESPONSIBILITIES

The medical establishment based at The Christie provides 5 Consultant Medical Oncologists, and 3+ Senior/Clinical Fellows within the ECM team. The medical establishment based at Peter MacCullum is integrated into the Department of Medical Oncology; with 7-8 of these Consultant Medical Oncologists acting as Principal Investigators in the Early Drug Development Program, along with 4 Early Drug Development Fellows integrated with the team.

Continuing Professional Development

The Trust supports the requirements for continuing professional development (CPD) as laid down by the GMC and surgical colleges and is committed to providing time and financial support for these activities.

Role Planning

ROLE: The successful candidate will be recruited as a Clinical Fellow/Senior Clinical Fellow in the Experimental Cancer Medicine Team. The candidate will then undertake the second part of the fellowship at The Peter MacCullum Cancer Centre in Melbourne. The Melbourne element of the fellowship will include a full job description relevant and relative to the Peter MacCullum Cancer Centre based role, and is structured in a similar manner to the role at The Christie.

RESEARCH: A diverse range of clinical research trials are in progress and, following training, the post holder will be expected to participate in these studies as a sub-investigator. These include phase I trials of small molecule inhibitors, next-generation chemotherapy trials, combination / multi-modality phase I trials, molecular characterisation / translational studies.

The post holder will be involved in managing all aspects of trial patients, through new patient consultation, consent and screening patients and reviewing patients at follow-up appointments. Primarily, patients are seen in the outpatient setting but with some inpatient cover. The appointee is required to attend 4-5 trial outpatient clinics per week (see indicative timetable).

The post holder will be expected to attend Safety Review Committee meetings (usually remotely) to discuss trial patients. This will involve close liaison with the trial Principal Investigators, referring consultant body across the Trust and other members of the team. In addition, the post-holder will interface with external stakeholders such as CROs and pharmaceutical sponsors.

The post-holder will be expected to attend monthly molecular tumour board meetings to discuss trial patients and to agree opportunities for patients to enroll in early phase trials.

PROTOCOLS: The post holder will be expected to undertake the administrative duties associated with the care of their patients. The appointee will be encouraged to harness opportunities to be involved in the development and planning of new studies.

Professional Development: The Clinical Fellow will maintain a level of continuing professional development consistent with the recommendations of the Royal College of Physicians. Appropriate arrangements for study leave will be made in conjunction with colleagues. There is the potential to present research work and the post holder will be expected to be involved in audit, writing papers and reviews. The post holder will also be required to undergo an annual appraisal.

Teaching Commitment:

a) Undergraduate

The appointee will be required to contribute to the undergraduate teaching of medical students on oncology topics.

b) Postgraduate

There is a busy postgraduate teaching programme and staff are often requested to lecture on relevant topics. The post holder will be expected to contribute actively to the education of junior doctors, specialty trainees and fellows on the team.

The post holder will also be expected to help in the training of nursing and multi-disciplinary staff in both in-patient and outpatient departments.

Clinical Governance: The post holder will be expected to participate in all relevant aspects of clinical governance, including maintaining up to date protocols, guidelines and clinical audit, under the supervision of the other consultants in the team.

Audit: The appointee will play a full role in clinical audit as a member of The Christie Medical Staff Committee. The appointee will develop, supervise and deliver team audit projects.

This is a 10 session non-training post funded through The Christie NHS Foundation Trust for an initial period of 1 year, to be followed by an additional year of the fellowship at The Peter MacCullum Cancer Centre in Melbourne with their Phase I/Early Drug Development team.

Provisional Sessional Timetable for Senior Clinical Fellow in Experimental Medicine

___________________________________________________________

Proposed Sessional Activities

Outpatient Clinics 5.0

Research Administration 2.0

Teaching 1.0

Trial Teleconferences 0.5

Team Meeting 0.5

Audit/CPD 1.0

10

A Sessional Activity is 4 hours

On call Commitments

This role does not require participation in the Trusts on-call rota.

PERSON SPECIFICATION

Essential for the post

Desirable for the post

METHOD OF ASSESSMENT

1. ATTAINMENTS

Educational

Completion of foundation training or acute care

common Stem programme (or

equivalent)

CCT in Medical or Clinical Oncology or equivalent.

Good Clinical Practice.

Advanced Life Support.

Higher degree in cancer research

AF

CE

Qualifications

MRCP or equivalent

Professional Qualifications

GMC registration

CE

Research / Publications

Evidence of productive ethical research relevant to oncology

Recent publications in peer-reviewed journals.

Conference presentations

AF

I

R

2. TRAINING

Experience in general

oncology and internal

medicine

Research/Trials experience

Experience in managing critically ill patients

AF

I

R

3. EXPERIENCE

Job Specific

Evidence of clinical leadership skills

Phase I trials experience

AF

I

R

Management / Audit

Experience of developing, supervising and delivering audit projects

AF

I

R

4. TEACHING

Experience in teaching undergraduates

Experience in teaching postgraduates.Teaching Qualification

AF

I

R

5. PERSONAL SKILLS

Evidence of clinical skills.

Excellent written and oral communication skills, flexibility, commitment and team work with colleagues and staff in the department; ability to work under pressure; capacity for staff motivation

Demonstration of excellent communication skills

AF

I

R

CE

6. CIRCUMSTANCES

Domicile

Occupational Health ClearanceEnhanced CRB Clearance

CE

Abbreviations for Methods of Assessment:

AF Application Form

I Interview

R References

CE Certification Evidence

Person Specification Qualifications Essential

• Completion of foundation training or acute care common Stem programme (or equivalent)
• GMC registration
• Evidence of productive ethical research relevant to oncology

Desirable

• CCT in Medical or Clinical Oncology or equivalent. Good Clinical Practice. Advanced Life Support. Higher degree in cancer research
• Recent publications in peer-reviewed journals. Conference presentations

CIRCUMSTANCES Domicile Essential

• Occupational Health clearance
• Enhanced CRB Clearance

Experience Essential

• Experience in general oncology and internal medicine
• Research/Trials experience
• Evidence of clinical leadership skills
• Experience of developing, supervising and delivering audit projects
• Experience in teaching undergraduates

Desirable

• Experience in managing critically ill patients
• Phase I trials
• Experience in teaching postgraduates. Teaching Qualification

PERSONAL SKILLS Essential

• Evidence of clinical skills.
• Excellent written and oral communication skills, flexibility, commitment and team work with colleagues and staff in the department; ability to work under pressure; capacity for staff motivation

Desirable

• Demonstration of excellent communication skills

Person Specification Qualifications Essential

• Completion of foundation training or acute care common Stem programme (or equivalent)
• GMC registration
• Evidence of productive ethical research relevant to oncology

Desirable

• CCT in Medical or Clinical Oncology or equivalent. Good Clinical Practice. Advanced Life Support. Higher degree in cancer research
• Recent publications in peer-reviewed journals. Conference presentations

CIRCUMSTANCES Domicile Essential

• Occupational Health clearance
• Enhanced CRB Clearance

Experience Essential

• Experience in general oncology and internal medicine
• Research/Trials experience
• Evidence of clinical leadership skills
• Experience of developing, supervising and delivering audit projects
• Experience in teaching undergraduates

Desirable

• Experience in managing critically ill patients
• Phase I trials
• Experience in teaching postgraduates. Teaching Qualification

PERSONAL SKILLS Essential

• Evidence of clinical skills.
• Excellent written and oral communication skills, flexibility, commitment and team work with colleagues and staff in the department; ability to work under pressure; capacity for staff motivation

Desirable

• Demonstration of excellent communication skills

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Additional information Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Employer details Employer name

The Christie NHS FT

Address

Research & Development - A00181

Manchester

M20 4BX

Employer's website

https://www.christie.nhs.uk/ (Opens in a new tab)

Employer details Employer name

The Christie NHS FT

Address

Research & Development - A00181

Manchester

M20 4BX

Employer's website

https://www.christie.nhs.uk/ (Opens in a new tab)