Senior Bioinformatician - Translational & Clinical Development

BioLizard; England; On-site; GBP 60,000 - 90,000; Part time

Job summary

A leading bioinformatics consultancy is seeking a Senior Bioinformatician for its England office to drive omics data integration in clinical development. The ideal candidate will have a PhD or Master's in Bioinformatics and 5-10 years of experience. Key responsibilities include data analysis, pipeline development, and ensuring compliance with regulations. Proficiency in R/Python and experience with omics data are essential. This contract role offers the opportunity to contribute to significant clinical projects.

Qualifications

• 5-10 years of relevant experience in clinical or translational bioinformatics.
• Strong expertise in analysis of patient-level omics data.
• Understanding of clinical study design and data privacy.
• Proficiency in R and/or Python.
• Proficiency in R and/or Python; experience with HPC, cloud, and containerization (e.g., Docker).
• Strong foundation in statistics, data mining, and visualization.
• Ability to work independently and deliver against deadlines, and to synergise within interdisciplinary teams.

Responsibilities

• Drive integration and interpretation of omics and clinical data.
• Develop bioinformatics pipelines tailored to data standards.
• Identify biomarkers of response and safety.
• Prepare reports and presentations for project teams.
• Ensure traceability and compliance with data governance, privacy, and quality standards in the clinical context.
• Prepare analytical reports, visualizations, and presentations for multidisciplinary clinical and project teams as well as scientific publications.
• Contribute to internal documentation, study reports, and scientific publications.

Skills

Bioinformatics

Data analysis

R and/or Python

Statistical analysis

Stakeholder management

Regulatory/compliant analysis

Communication

Team collaboration

Education

PhD or Master’s degree in Bioinformatics or related field

Tools

HPC

Docker

Cloud computing

Job description

Senior Bioinformatician – Translational & Clinical Development

BioLizard is a leading bioinformatics consultancy partner for biotech and pharma organizations, helping to bridge biology, data, and AI. Our mission is to unlock insights that accelerate scientific innovation and clinical translation. As a BioLizard consultant, you’ll work on‑site in the UK or Belgium, embedded as part of the bioinformatics team of a key pharma client, supporting Translational and Clinical Development and contributing to development programmes that bring novel therapies to patients.

We are also seeking a second candidate at a more junior level to join this team.

Role Description

You will drive the integration and interpretation of omics, translational and clinical data from patient studies to identify biomarkers, assess mechanisms of action, and inform clinical decision‑making.

Key Responsibilities

• Process, analyze, and interpret molecular datasets from clinical studies, including bulk and single‑cell transcriptomics, spatial transcriptomics, proteomics, and epigenomics.
• Develop robust, reproducible bioinformatics pipelines tailored to patient‑level data and regulatory standards.
• Apply methods for pathway and network analysis, functional enrichment, and causal reasoning to derive clinical insights.
• Integrate omics and clinical variables to identify biomarkers of response, safety, or stratification.
• Ensure traceability and compliance with data governance, privacy, and quality standards in the clinical context.
• Prepare analytical reports, visualizations, and presentations for multidisciplinary clinical and project teams as well as scientific publications.
• Contribute to internal documentation, study reports, and scientific publications.

Qualifications – Essential

• PhD or Master’s degree in Bioinformatics, Computational Biology, or related field, with 5–10 years of relevant experience in clinical or translational bioinformatics in a business context.
• Strong expertise in analysis of patient‑level omics data (bulk/single‑cell RNA‑seq, proteomics, epigenomics, spatial data).
• Understanding of clinical study design, data privacy, and regulatory‑compliant analysis.
• Proficiency in R and/or Python; experience with HPC, cloud, and containerization (e.g., Docker).
• Strong foundation in statistics, data mining, and visualization.
• Ability to work independently and deliver against deadlines, as well as to synergise within interdisciplinary teams, enabling and empowering them to deliver high‑quality scientific results. Excellent written and verbal communication skills and the ability to engage both scientific and clinical audiences. Excellent stakeholder management is essential.

Qualifications – Preferred

• Experience integrating omics with clinical and phenotypic data to inform biomarker hypotheses.
• Familiarity with FAIR data principles, reproducible research, and GxP environments.
• Understanding of disease biology (neurology, immunology, rare disease) for contextual interpretation.
• Track record of contributions to peer‑reviewed publications or clinical project reports.

Further Information

• Seniority level: Mid‑Senior level
• Employment type: Contract
• Job function: Research, Analyst, and Information Technology