Senior Bioinformatician/Data Scientist

Wellcome Sanger Institute; Uttlesford; Hybrid; GBP 44,000 - 52,000; Full time

Job summary

A leading research institute in the UK is seeking a Senior Bioinformatician/Data Scientist to lead key analyses in human health research. You will work on large multiomic datasets, design and scale analytical pipelines, and mentor junior staff. The ideal candidate will have a degree in a relevant field and substantial experience with genetic/genomic data, programming in Python and R, and high-performance computing environments. The position is hybrid and offers a competitive salary between £44,905 and £52,000, based on experience.

Benefits

Comprehensive wellbeing program

Flexible working arrangements

Qualifications

• Experience with large-scale genetic/genomic data.
• Proficiency with relational databases (e.g., MySQL), programming in Python and R.
• Unix experience in high-performance computing.

Responsibilities

• Design analytical pipelines and collaborate with team members.
• Assist with data analysis, reporting, and contribute to publications.
• Enhance data management practices and systems.

Skills

Bioinformatics

Computer Science

Data Analysis

Python

R

Unix

Version Control

Pipeline Creation

Education

Degree or equivalent in Bioinformatics, Biostatistics, Computer Science, Mathematics, Statistics, or Life Sciences

Tools

MySQL

GitHub

NextFlow

Job description

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Senior Bioinformatician/Data Scientist, Saffron Walden

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Job Reference:

630d2fd16bd3

Job Views:

6

Posted:

12.08.2025

Expiry Date:

26.09.2025

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Job Description:

Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity's greatest challenges.

We are looking for a Senior Data Scientist/Bioinformatician, experienced in handling large multiomic datasets, to lead key analyses, support and mentor junior scientists, and curate our data repository for 12 months, covering maternity leave.

About the Role:

The work involves developing, scaling pilot analyses, creating new pipelines and tools, and optimizing existing pipelines.

What you will do:

• Design analytical pipelines and collaborate with team members to automate and scale them.
• Assist with data analysis, reporting, and contribute to publications.
• Enhance data management practices and systems.
• Develop and maintain genetic, genomic, and phenotypic data databases following best practices.
• Prepare data extracts, document data releases.
• Coordinate with research administrators and DNA pipelines team for sample prioritization and status updates.
• Manage and archive data with the team, oversee storage capacity.
• Ingest external data relevant to research goals.

About You:

You will establish best practices for analyzing genetic (WGS, WES, genotyping arrays), genomics (RNAseq, single-cell, spatial transcriptomics), and phenotypic data from thousands of participants, designing and scaling analyses, automating pipelines, and working in high-performance computing environments.

You will ensure data is uploaded to repositories, secure, and accessible to external users, and handle external datasets documentation and alignment.

You will contribute to scientific publications, collaborate actively, and mentor junior scientists.

Essential Skills:

• Degree or equivalent in Bioinformatics, Biostatistics, Computer Science, Mathematics, Statistics, or Life Sciences.
• Experience with large-scale genetic/genomic data.
• Proficiency with relational databases (e.g., MySQL), programming in Python and R.
• Unix experience in high-performance computing.
• Experience with version control platforms (e.g., GitHub).
• Pipeline creation experience, preferably with NextFlow.
• Good organizational and prioritization skills.
• Attention to detail and accuracy.
• Effective communication skills.
• Ability to work collaboratively in an inclusive environment.

About Us:

The Genomics of Inflammation and Immunity Group at the Wellcome Sanger Institute, led by Dr. Carl Anderson, comprises statisticians, geneticists, immunologists, computer scientists, and clinicians studying immune-mediated diseases.

You will lead analyses, develop tools, optimize pipelines, and integrate genetic and phenotypic data in a large-scale research program on immune diseases.

Other Information:

Application Process: Submit your CV and cover letter explaining your suitability, motivation, and value addition, addressing technical and behavioral skills.

Salary: £44,905 - £52,000 per annum, depending on skills and experience.

Closing date: 19th August 2025.

Hybrid Working: We support flexible working arrangements tailored to roles and teams to promote work-life balance and collaboration.

Equality, Diversity and Inclusion: We promote an inclusive culture, supporting various staff networks, and are committed to non-discriminatory recruitment and development.

Our Benefits: We offer a comprehensive wellbeing program and are committed to supporting technicians through the Technicians Commitment.