Senior AI/ML Bioinformatician

Francis Crick Institute Ltd; Greater London; On-site; GBP 46,000 - 63,000; Full time

Benefits offered by this job

Visa sponsorship

Annual leave 28 days

Pension scheme

Health & well-being services

On-site restaurant

Discounted gym memberships

Social spaces

Job summary

The Francis Crick Institute in London seeks a Senior AI/ML Bioinformatician to apply advanced AI/ML methods to biomedical datasets, partnering with researchers to design analyses and deliver actionable insights.

You will develop bespoke analysis pipelines, mentor colleagues, and contribute to high-impact publications while working in a collaborative, technology-driven environment.

Qualifications

• A degree in a relevant subject with an extensive analytical component e.g. bioinformatics, statistics, molecular biology or mathematics.
• Significant experience with varied types of biomedical data and analysis.
• Extensive experience applying AI/ML bioinformatics to multiple concurrent projects in a collaborative biological research environment to provide publication-quality analysis results to researchers.
• Significant experience in Agentic AI and LLM applied to biomedical research.
• Significant experience in R or Python with a track record of developing programs and scripts conforming to common coding standards.

Responsibilities

• Provide AI/ML expertise to help Francis Crick scientists achieve their research objectives.
• Provide expertise to inform on the experimental and analysis design process.
• Analyse complex biomedical data, using a wide range of biological resources, as well as Agentic AI, LLM and AI/ML methods to deliver on complex bespoke analysis goals.
• Interpret, evaluate and apply novel analysis approaches to build bespoke analysis tools to solve analysis questions.
• Apply analysis expertise to help scientists interpret results and make research decisions.
• Work independently at all points of the data analysis workflow.
• Help to develop others by mentoring and sharing expertise and experience: fellow team members with your specific skillsets, as well as biologists by coaching them to deliver specialised analysis.
• Help to support and develop group project management and reporting procedures.

Skills

AI/ML

Bioinformatics

Collaborative research

Python

R

LLM

Agentic AI

HPC

Education

Degree in bioinformatics or related field

Tools

Python

R

HPC

LLM tooling

Job description

Salary for this Role: From £54,620 with benefits, subject to skills and experience

Job Title: Senior AI/ML Bioinformatician Reports to: Probir Chakravarty Closing Date: 04/Oct/2026 23.59 GMT

Job Description: Job Title: Senior AI/ML Bioinformatician Details of the role: Reporting to: Principle Laboratory Research Scientist - Bioinformatics & Biostatistics Platform Working pattern: This is a full-time, permanent position on Crick terms and conditions of employment. Salary: From £54,620 per annum with benefits, subject to skills and experience. Application closing date: 4th of October 2026 at 23:59

About us

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We’ve removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.

About the role

We are looking for a collaborative and self-motivated Senior Bioinformatician with extensive AI/ML experience analysing biomedical data in a research environment to join the Bioinformatics and Biostatistics team. You will collaborate with leading scientists to analyse complex biological datasets, uncover new insights, and accelerate discoveries that improve human health. This is an exciting opportunity for an experienced and innovative researcher to apply advanced computational approaches across a diverse range of scientific projects while contributing to a collaborative, technology-driven research environment.

The Project

As a Senior Bioinformatician, you will partner with researchers across the Francis Crick Institute to provide advice and analyses of complex omics, imaging, and clinical datasets, turning data into meaningful biological insights. You’ll play an active role in shaping experimental design, developing innovative analytical approaches, and delivering impactful discoveries. Working within a highly collaborative team, you will also have opportunities to publish research, build bespoke analysis pipelines, and mentor others, making a lasting contribution to both scientific advancement and capability development.

What you will be doing

• You will Provide AI/ML expertise to help Francis Crick scientists achieve their research objectives.
• Provide expertise to inform on the experimental and analysis design process.
• Analyse complex biomedical data, using a wide range of biological resources, as well as Agentic AI, LLM and AI/ML methods to deliver on complex bespoke analysis goals.
• Interpret, evaluate and apply novel analysis approaches to build bespoke analysis tools to solve analysis questions.
• Apply analysis expertise to help scientists interpret results and make research decisions.
• Work independently at all points of the data analysis workflow.
• Help to develop others by mentoring and sharing expertise and experience: fellow team members with your specific skillsets, as well as biologists by coaching them to deliver specialised analysis.
• Help to support and develop group project management and reporting procedures.

About you

• A degree in a relevant subject with an extensive analytical component e.g. bioinformatics, statistics, molecular biology or mathematics.*
• Significant experience with varied types of biomedical data and analysis.
• Extensive experience applying AI/ML bioinformatics to multiple concurrent projects in a collaborative biological research environment to provide publication-quality analysis results to researchers*
• Significant experience in Agentic AI and LLM applied to biomedical research.*
• Significant experience in R or Python with a track record of developing programs and scripts conforming to common coding standards.
• Experience in applying expertise to the experimental and analysis design process.
• Proven ability to communicate analytical and computational insights clearly to biological and clinical audiences. (desirable)
• Familiarity with the application of statistical techniques to biological data (desirable)
• Excellent computational skills applied to HPC, big data, software development, version control and web technologies. (desirable)
• Minimum criteria*

About Working at the Crick

Our values Everyone who works at the Crick has a valuable role to play in advancing the Crick’s mission and shaping our culture. We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We’re not afraid to do things differently. We are open. We’re highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We are a Disability Confident: Committed employer and want to ensure that everyone can apply and be part of our recruitment processes and so we'll make reasonable adjustments if you need them - just let us know when you apply. If you need assistance with applying (i.e., would like to apply by phone or post)please email: [e-mail]

What will you receive?

• Visas: Applicants for this role will be eligible for sponsorship to work in the UK
• Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays.
• Pension Scheme: Defined contribution pension with employer contributions of up to 16%.
• Health & Well-being: 24/7 GP consultation services.
• Occupational health services and mental health support programs.
• Eye care vouchers and discounted healthcare plans.
• Work-Life Balance: Back-up care for dependents.
• Childcare support allowance.
• Annual leave purchase options.
• Crick Networks offering diverse groups' support, community and inclusive social events.
• Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts.
• Subsidised on-site restaurant and social spaces for team interaction.

Please note you must meet the essential criteria listed within the Role Profile, to have your application reviewed.