Scientist, Research & Development

Jazz Pharmaceuticals; Sittingbourne; On-site; GBP 40,000 - 55,000; Full time

Job summary

A global biopharma company is seeking an R&D Scientist in Sittingbourne to perform solid-state characterization and collaborate on drug development. Candidates should hold a Bachelor’s degree in pharmaceutical sciences and possess hands-on experience with characterization techniques. An innovative mindset and attention to detail are essential for success. Competitive benefits include medical insurance and flexible paid vacation.

Benefits

Medical insurance

Dental insurance

Vision insurance

Retirement savings plan

Flexible paid vacation

Qualifications

• Strong knowledge of statistical principles.
• Proactive problem-solving skills.
• Ability to execute follow-up experiments.

Responsibilities

• Perform solid-state characterization activities.
• Conduct solubility and dissolution experiments.
• Collaborate with teams on solid-state experiments.
• Maintain lab safety and cleanliness.

Skills

High level of numeracy

Excellent writing and presentation skills

Attention to detail

Collaborative team player

Hands-on experience with DSC, TGA, DVS, XRPD, SEM

Education

Bachelor’s degree in pharmaceutical sciences

Master’s degree in pharmaceutical sciences

Tools

HPLC-UV

Job description

If you are a current Jazz employee please apply via the Internal Career site.

Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit www.jazzpharmaceuticals.com for more information.

The R&D Scientist will be performing the solid-state characterization of our lead assets across the company’s entire discovery portfolio. The individual will also collaborate with the rest of the team in the development and assessment of our formulations intended for preclinical and first-in-human administration

Essential Functions

• Carry out comprehensive solid-state characterization activities to advance lead assets from early discovery through to first in human
• Carry out solubility and dissolution experiment to assess the stability and predict the bio-performance of our internal formulations
• Collaborate with the cross-functional team to design and execute solid-state experiments, crystallisation and polymorph screens, and analyses to provide fundamental understanding of drug substance and drug product stability
• Document experimental procedures in accordance with existing standard operating procedures and best practices.
• Comply with all relevant safety and GxP procedures
• Demonstrate competency and innovation on a range of complex laboratory skills and equipment
• Maintain industry knowledge and keep abreast of relevant new technologies.
• Contribute to process driven continuous improvements initiatives
• Record and review all experimental outcomes in an appropriate format
• Report and communicate project outcomes in an appropriate manner
• Identify and resolve promptly problems occurring at any phase of a study, escalating to the line manager where necessary
• Maintain all areas of the laboratory in clean and tidy state.
• Responsible for maintaining cGxP and Health and Safety knowledge relevant to the role
• Develop and maintain positive working relationships with others
• Share ideas and information
• Assist colleagues when required
  
  

Required Knowledge, Skills, And Abilities

• High level of numeracy, and awareness of basic statistical principles
• Excellent writing and presentational skills
• Excellent attention to detail, pro-active approach to problem solving.
• Uses own judgment to execute follow-up experiments, including troubleshooting
• Collaborative team player
• Knowledge and hands on experience in any of the following techniques: DSC, TGA, DVS, XRPD, SEM, PSD, HPLC-UV, thermodynamic solubility assessment, polymorph screen
  
  

Required/Preferred Education And Licenses

• Bachelor’s degree (or equivalent) in pharmaceutical sciences, chemistry, chemical engineering or material sciences
• Master’s degree (or equivalent) in pharmaceutical sciences, chemistry, chemical engineering or material sciences
  
  

Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law.

The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: https://careers.jazzpharma.com/benefits.html.