Scientist - Multicellular Disease Models - 12 month contract

Relation; London; On-site; GBP 100,000 - 125,000; Full time

Job summary

A leading biotech company in London is seeking a Scientist to join their experimental laboratory for a 12-month contract. The successful candidate will support target validation experiments and contribute to drug discovery initiatives, working alongside a talented interdisciplinary team. This role offers the opportunity to impact patients' lives through innovative research in drug development.

Qualifications

• Demonstrable experience in assay development and/or target validation.
• Experience with mammalian cellular models and multicellular assays.
• Ability to work within cross-functional teams.

Responsibilities

• Contribute to projects focused on understanding novel target biology.
• Design and establish 3D multicellular models.
• Generate and analyze biological data for drug discovery projects.

Skills

Assay development

Target validation

Cellular and molecular biology

Gene editing

Collaboration

Education

PhD

Tools

CRISPR/Cas9

Flow cytometry

Fluorescence microscopy

RT-qPCR

Job description

Scientist - Multicellular Disease Models – Target Validation, 12 month contract

London

About Relation

Relation is an end-to-end biotech company developing transformational medicines, with technology at our core. Our ambition is to understand human biology in unprecedented ways, discovering therapies to treat some of life’s most devastating diseases. We leverage single-cell multi-omics directly from patient tissue, functional assays, and machine learning to drive disease understanding—from cause to cure.

This year, we embarked on an exciting dual collaboration with GSK to tackle fibrosis and osteoarthritis, while also advancing our own internal osteoporosis programme. By combining our cutting-edge ML capabilities with GSK’s deep expertise in drug discovery, this partnership underscores our commitment to pioneering science and delivering impactful therapies to patients.

We are rapidly scaling our technology and discovery teams, offering a unique opportunity to join one of the most innovative TechBio companies. Be part of our dynamic, interdisciplinary teams, collaborating closely to redefine the boundaries of possibility in drug discovery. Our state-of-the-art wet and dry laboratories, located in the heart of London, provide an exceptional environment to foster interdisciplinarity and turn groundbreaking ideas into impactful therapies for patients.

We are committed to building diverse and inclusive teams. Relation is an equal opportunities employer and does not discriminate on the grounds of gender, sexual orientation, marital or civil partner status, gender reassignment, race, colour, nationality, ethnic or national origin, religion or belief, disability, or age. We cultivate innovation through collaboration, empowering every team member to do their best work and reach their highest potential.

By joining Relation, you will become part of an exceptionally talented team with extraordinary leverage to advance the field of drug discovery. Your work will shape our culture, strategic direction, and, most importantly, impact patients’ lives.

Opportunity

We have an exciting opportunity for a Scientist to join Relation’s cutting-edge experimental laboratory and contribute to our drug discovery initiatives. The successful candidate will be supporting and executing target validation experiments, generating and interpreting scientific data, and supporting the maintenance of the laboratory. Your contributions will be part of advancing our research and ensuring successful project outcomes.

As part of the Relation team, you will join a team of talented professionals, including wet-lab scientists and data scientists and gain exposure to a diverse range of skills, both in and outside of your primary area of expertise.

Your responsibilities

• Scientist proficient in cellular and molecular biology to contribute to projects focused on understanding novel target biology

• Work within the team to design, optimise and establish 3D multicellular and other complex cellular models that closely mimic human tissue architecture and disease states to permit the interrogation of novel target biology.

• Contribute to orthogonal validation projects by maintenance of cell lines, utilisation of CRISPR/Cas9 gene editing & microscopy endpoints

• Generate, analyse & contribute biological data to Relations novel drug discovery projects.

• Working as a member of the lab team to ensure efficient running of the lab, including a variety of responsibilities as required.

Professionally, you have

• A PhD with demonstrable experience in assay development and/or target validation.

• Experience with a variety of mammalian cellular models including established cell lines, patient-derived primary cells and the development of 2D or 3D multicellular assays, with functional disease relevant endpoints with the aim of ensuring required reproducibility and sensitivity in those assays.

• Experience using multi-parameter endpoints including, but not limited to flow cytometry, fluorescence microscopy, plate based fluorescent assays, soluble ligand analysis, RT-qPCR.

• Knowledge of gene editing tools (e.g., CRISPR/Cas9) and RNA interference for modulating gene expression in 2D and 3D cell systems.

• A proven ability to work closely within cross-functional teams to progress target validation projects and present findings to internal stakeholders.

Desirable knowledge or experiences

• Comfortable working in a Biotech environment

• Ability to multitask and effectively contribute to projects in response to changing priorities

Personally, you are

• A collaborative team player.

• A clear and effective communicator.

• Driven by the impact of preclinical development

• Motivated to stay at the forefront of scientific advancements.

• Passionate about contributing to meaningful advancements in healthcare.

Join us in this exciting role, where your contributions will directly impact advancing our understanding of genetics and disease risk, supporting our mission to deliver transformative medicines to patients. Together, we’re not just conducting research—we’re setting new standards in the fields of machine learning and genetics. The patient is waiting!

Relation is a committed equal opportunities employer.

Note - This position is available as a contractor role via Hlx Life Sciences' services (inside IR35), remunerated on a daily rate.

RECRUITMENT AGENCIES: Please note that Relation does not accept unsolicited resumes from agencies. Resumes should not be forwarded to our job aliases or employees. Relation will not be liable for any fees associated with unsolicited CVs.