Scientist II: Analytical Development

ZipRecruiter; Cambridge; On-site; GBP 30,000 - 45,000; Full time

Job summary

A leading biotech company in Cambridge is seeking an analytical scientist to develop and validate methods for characterizing synthetic DNA and enzymes. The role involves working closely with R&D teams, applying various analytical techniques, and ensuring compliance with regulatory standards. Ideal candidates should have a relevant degree and hands-on lab experience.

Benefits

Competitive salary

Private healthcare

Pension contributions

Life assurance

Qualifications

• 2+ years of relevant industry experience.
• Hands-on experience in biology or chemistry labs.
• Experience in troubleshooting new assays and techniques.

Responsibilities

• Design, develop, and validate analytical assays for enzyme characterization.
• Implement assays to assess enzyme activity and molecular integrity.
• Analyze and interpret experimental data; solve experimental problems.

Skills

Analytical techniques

Team working

Communication

Enzyme characterization

Data analysis

Education

MSc in biochemistry, chemistry or related field

BSc in biological/chemical sciences

Tools

PCR

qPCR

ELISA

CGE

HPLC

Nanodrop

Qubit

SDS-PAGE

Western blotting

BCA

Job description

Job Description

4basebio is an innovative gene synthesis company with the ambition to provide high quality, synthetic DNA for use in gene therapy and gene editing platforms. We are starting our DNA analytic facilities at our site in Cambridge, UK and are looking for dynamic and experienced team members to help us achieve our ambitions and goals.

The role will focus on the development of new methods for the analysis of our novel, synthetic DNA products for customer and discovery projects. It will be also focus on the development of analytical tools to characterize enzymes and other biomolecules that works as raw materials for DNA synthesis. The candidate will have opportunity to interact with multi-disciplinary teams within the R&D department and expand their laboratory skill set.

Key Responsibilities:

• Design, develop, and validate analytical assays for enzyme characterization, DNA, RNA, and other biomolecules.
• Implement assays such as PCR, qPCR, ELISA, and gel electrophoresis to assess enzyme activity and molecular integrity essential.
• Develop analytical methods and carry out laboratory analysis using a range of techniques including CGE and HPLC.
• Work in collaboration with R&D for the development of new analytical methods for nucleic acids and proteins.
• Ensure assays meet regulatory standards and are suitable for QC testing and product release.
• Analyse and interpret experimental data; identify and solve experimental problems.
• Use and maintain company equipment in accordance with the company’s SOPs and health & safety guidelines.
• Keep up to date with relevant scientific and technical developments.
• Establish and maintain a detailed record of all the experiments and results generated in the lab.

Person Specification:

• MSc in biochemistry, chemistry, or related life science field or BSc in biological/chemical sciences, or a related discipline with relevant industry experience (2+ Years).
• Hands-on experience working in biology or chemistry labs.
• Experience in analytical techniques for nucleic acids characterization and quantification: Nanodrop, Qubit, , CGE, sequencing.
• Experience in analytical techniques for proteins characterization and quantification: SDS-PAGE gels, silver staining, western blotting, plate-based assays (ELISA, enzymes activity assays, BCA)
• Expertise handling LC systems.
• Experience in tech transfer documentation .
• Ability to test and troubleshoot new assays and techniques.
• Excellent team working and communication skills.
• Must have the right to work in the UK

What we can offer: Competitive salary + private healthcare + pension contributions + life assurance

Location: Over, Cambridge

To apply for this role send you CV and covering letter to [e-mail]

Due to the high number of applicants, if you do not hear back from us within 6 weeks, we thank you for your interest, but please assume you have not been selected for interview on this occasion.