Scientist I/II - Integrative Biology Cambridge

Sail Biomedicines, Inc.; Cambridge; On-site; GBP 30,000 - 50,000; Full time

Job summary

A leading company in programmable medicines is seeking a Scientist I/II to join their Integrative Biology team. The role focuses on developing assays for RNA medicines, requiring a PhD and strong experimental skills. The successful candidate will collaborate within a fast-paced environment, contributing to innovative therapeutic discoveries.

Qualifications

• PhD in immunology, microbiology or closely related field.
• Strong background in experimental design and data analysis.
• Proficiency in developing and performing serology and cell-based assays.

Responsibilities

• Build Sail’s core technological platform and discover novel therapeutics.
• Optimize and standardize serology and molecular assays.
• Generate endpoint data for in vivo studies.

Skills

Experimental Design

Data Analysis

Effective Communication

Serology Assays

Cell-Based Assays

Education

PhD in Immunology

PhD in Microbiology

Tools

Flow Cytometry

ELISA

Luminex Assays

Job description

Title: Scientist I/II Integrative Biology

Manager:Principal Scientist, Integrative Biology

Type: Onsite

About Sail:

Sail Biomedicines is harnessing evolutionary and artificial intelligence to revolutionize programmable medicines. Sail’s platform combines first-in-class programmable RNA technology (Endless RNATM or eRNA), and an industry-leading platform of programmable nanoparticles, utilizing natural components, to unlock comprehensive programming of medicines for the first time. By leveraging cutting-edge eRNA and nanoparticle deployment technology, Sail is building a wealth of data, enabling unparalleled use of AI techniques to identify and design fully programmable medicines that are potent, targeted, versatile, and tunable. Sail was founded by Flagship Pioneering.

The Role:

Sail Biomedicines is seeking a highly motivated Scientist I/II to join the Integrative Biology group at Sail Biomedicines.Collaboratingwith an interdisciplinary team experiencedinmolecular biology, bioengineering, pharmacology, data science, and machine learning,this individual willdevelop andscalerobust assaystodiscoverthenext generationofRNA medicines.The ideal candidatewill bring a track record of scientific initiativeanda deep commitment toteamworktothe Integrative Biology group’s fast-paced culture of scientific rigor.

This lab-based onsite position requires the majority of time to be dedicated to hands-on lab work, focusing on experimental tasks and collaboration within the team to drive project success.

Responsibilities:

• Help us build Sail’s core technological platform and discover novel therapeutics.
• Operate outside your scientific comfort zone to lead and support multiple projects from ideation through execution.
• Optimization and standardization of serology and molecular assays
• Generate endpoint data for in vivo studies including, but not limited to flow cytometry and molecular assay readouts
• Assist other team members in performing laboratory experiments as needed
• Maintain accurate and up to date laboratory notebooks

Qualifications:

• PhD in immunology, microbiology or a closely related field.
• Strong background in experimental design, data analysis, and interpretation.
• Effective communication with both technical and non-technical audiences.
• Proficiency in developing and performing serology and cell-based assays.
• Ability to work effectively with minimal direction and oversight.

Desired Qualifications:

• Experience in conducting preclinical vaccine studies and processing animal tissue samples
• Experience in cell and tissue culture experiments, serology assays (ELISAs, bead-based Luminex assays), T cell assays (flow cytometry based immunophenotyping, intracellular cytokine assays and ELISPOT). Experience with automation would be an asset.
• Solid grounding in data analysis and statistics

Sail Biomedicines is an Equal Opportunity Employer. Sail does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, national origin, veteran status, or any other status protected under federal, state, or local law.

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