Scientist – Early Respiratory & Immunology

TN United Kingdom; London; On-site; GBP 60,000 - 100,000; Full time

Job summary

An established industry player is seeking a passionate Associate Principal Scientist to join their Early Respiratory & Immunology team. This role involves characterizing neuronal reflex mechanisms in airway diseases and executing innovative bioscience experiments. With a focus on collaboration, you'll work alongside leading scientists to advance research in chronic diseases like asthma and COPD. The company promotes a culture of learning and innovation, offering a supportive environment where your contributions can make a real difference in patient care. If you're eager to tackle complex challenges and drive scientific breakthroughs, this opportunity is for you.

Qualifications

• 5+ years postdoctoral/industrial experience required.
• Strong publication record and presentation experience.

Responsibilities

• Characterising mechanisms driving neuronal reflexes in airway diseases.
• Designing and executing bioscience experiments.

Skills

Neuronal reflexes

Electrophysiological recording techniques

Biochemical techniques

Cellular imaging

Molecular techniques

Training and mentoring

Education

PhD in a relevant scientific discipline

Tools

qPCR

ELISA

Western blot

Job description

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Scientist – Early Respiratory & Immunology, London

Client:

Location: London, United Kingdom

Job Category: Other

EU work permit required: Yes

Job Reference:

fe9aa1d76915

Job Views:

11

Posted:

26.04.2025

Expiry Date:

10.06.2025

Job Description:

R-203168: Associate Principal Scientist - Early Respiratory & Immunology

Imperial College, London

Competitive Salary & Excellent Benefits

Introduction to role:

Join AstraZeneca in the Early R&I (Respiratory and Immunology) department, aiming for early intervention, durable remission, disease modification, and cure of chronic diseases. We seek passionate scientists eager to make a difference!

We are looking for experienced senior researchers with expertise in neuronal reflexes and respiratory diseases to join our Bioscience team at Imperial College, London.

What you’ll do

You will focus on characterising mechanisms driving neuronal reflexes in airway and immunological disease, designing and executing bioscience experiments, collaborating with team leaders, and reporting scientific activities. The role may require working outside regular hours to meet project timelines.

• A PhD or equivalent in a relevant scientific discipline with 5+ years postdoctoral/industrial experience.
• Experience in extracellular electrophysiological recording techniques in airway sensory nerves.
• Knowledge of afferent single fibre techniques.
• Understanding of biological pathways in respiratory diseases like asthma, COPD, and IPF.
• Current PIL license with experience in in vivo studies respecting the 3Rs.
• Experience with human biological samples and relevant regulations.
• Cellular imaging and recording techniques in primary cells.
• Innovation in new technologies and methods.
• Strong publication record and presentation experience.
• Experience in training, supervision, and mentoring.
• Highly organized, self-motivated, capable of working independently and in teams.
• Understanding of key biological pathways in immunological diseases.
• Proficiency in biochemical and molecular techniques: primary cell culture, qPCR, protein expression, ELISA, Western blot, etc.

We promote in-person collaboration, working at least three days a week in the office/lab, with flexibility to respect individual needs. Join our ambitious team!

Why AstraZeneca?

We follow science to innovate and aim to treat, prevent, modify, and cure complex diseases. Our pipeline growth and global impact are driven by data, technology, and scientific breakthroughs.

Join us to learn, innovate, and build a meaningful career, delivering life-changing medicines based on real patient needs.

Next Steps

This advert runs from Monday, 24th June 2024. We encourage early applications. The closing date is Friday, 28th June 2024.

Where can I find out more?

• This is what we’re made of:
• Our sustainability ambition:
• Recent Publications:

Date Posted: 24-Jun-2024

Closing Date: 28-Jun-2024

We are committed to an inclusive environment. Applications are welcome from all qualified candidates. Reasonable adjustments are available upon request.