Scientist/Associate Scientist, In vivo pharmacology

ZipRecruiter; Cambridge; On-site; GBP 40,000 - 80,000; Full time

Job summary

An established industry player is seeking a passionate Scientist to support innovative drug discovery efforts targeting antibody-driven diseases. This role involves designing and executing in vivo experiments, managing pharmacology studies, and contributing to the development of cutting-edge therapies. The ideal candidate will possess a strong background in immunology and drug discovery, with a proven ability to work collaboratively in a dynamic environment. Join a forward-thinking team dedicated to transforming treatment paradigms and making a significant impact in the field of precision medicine.

Qualifications

• PhD with 0-3 years or Bachelor's with 8+ years in immunology or cell biology.
• Experience in in vivo studies and ex vivo sample analysis.

Responsibilities

• Design and conduct in vivo biology experiments for preclinical drug discovery.
• Manage CRO-based workflows and collaborate with team leads.

Skills

Immunology

Biologics Drug Discovery

Data Analysis

Communication Skills

Problem-Solving Skills

Education

PhD in Relevant Scientific Area

Masters in Relevant Scientific Area

Bachelor's in Relevant Scientific Area

Tools

ELISA

Flow Cytometry

Job description

At Merida Biosciences, we are pioneering true precision medicines for antibody-driven diseases. We specifically target pathogenic antibodies and their cellular sources with bespoke Fc biotherapeutics engineered to selectively and completely eliminate the root causes of autoimmune and allergic diseases, and to achieve deep, durable responses while preserving essential immunity. We are looking for passionate individuals to join our mission to transform treatment paradigms across the spectrum of antibody-driven diseases.

The Scientist/AS will support the in vivo pharmacology team for discovery-stage pipeline program(s) focused on antibody-driven diseases. The role will work collaboratively with the Biology team lead(s) to contribute to lead characterization and development candidate selection. The Scientist/AS will aid in the management of both external and internal in vivo pharmacology studies and contribute to the growth of internal in vivo capabilities. The ideal candidate is an experienced lab-based biologist with a background in immunology and biologics drug discovery.

Responsibilities:

• Design and carry out in vivo biology experiments that support preclinical drug discovery including PK/PD analysis, mechanism of action studies, and disease modeling
• Aid in expanding our internal in vivo pharmacology capabilities at a shared vivarium space, including animal handling, dosing, and sample collection/processing
• Independently develop and execute quantitative assays for the analysis/characterization of ex vivo samples (ELISA, flow cytometry, etc.)
• Work collaboratively with peer team leads to advance program(s) to IND
• Proactively review literature to bring in newest scientific findings, ideas, and methods/technologies for discovery research
• Manage out-sourced CRO-based workflows, including study design and data analysis

Requirements:

• PhD with 0-3 years or a Bachelors with 8+ years or Masters with 6+ years in relevant scientific area, such as immunology, cell/molecular biology
• Experience in the design and execution of in vivo studies (experience assessing pharmacokinetics/pharmacodynamics of biologics)
• Experience with ex vivo sample analysis and data interpretation (ELISA, immunophenotyping)
• Capacity to work within a dynamic matrix environment, with strong contributions to project strategy and execution
• Excellent communication, presentation, and inter-personal skills; superb organizational and problem-solving skills

Merida Biosciences is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of veteran status, or any classification protected by federal, state, or local law.