Scientist Analytical Development & Validation - Oxford

ZipRecruiter; Oxford; On-site; GBP 40,000 - 60,000; Full time

Job summary

A leading company in biotechnology seeks a Scientist for Analytical Development in Oxford. This role involves developing and qualifying analytical methods for biopharmaceuticals, requiring strong industry experience and a relevant degree. The successful candidate will thrive in a collaborative innovative environment focused on improving patient outcomes.

Qualifications

• At least 2 years of industry experience in analytical development or QC.
• Hands-on expertise with HPLC/UHPLC techniques for protein analysis.
• Knowledge of GMP principles and assay qualification/validation.

Responsibilities

• Develop and qualify UHPLC and gel/capillary electrophoresis methods.
• Evaluate novel analytical techniques for platform development.
• Prepare and review study protocols and reports.

Skills

HPLC/UHPLC techniques

Electrophoretic methods

Record-keeping

Self-learning

Education

BSc or MSc in biochemistry

PhD in a related discipline

Job description

Job Description

Scientist Analytical Development & Validation - Oxford Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company dedicated to developing transformative medicines for unmet patient needs in oncology, infectious diseases, and autoimmune diseases. Our R&D leaders are internationally recognized as some of the biotech industry's most successful drug developers. We foster an environment where collaboration, innovation, and scientific excellence thrive.

Our focus is on delivering first-in-class biological therapies. We have developed an innovative soluble TCR platform and ImmTAX molecules that harness the immune system to treat a broad spectrum of diseases. At Immunocore, our employees are our greatest asset, and we are committed to an inclusive workplace that values diversity and equal opportunity.

We encourage applications from individuals of all backgrounds. Successful candidates will join a dynamic team developing analytical methods to support our expanding pipeline of biopharmaceuticals. The core responsibilities include developing and transferring chromatography and electrophoresis-based methods for lot release and stability testing, and providing analytical expertise for program development both internally and with CDMO partners.

Key Responsibilities:

1. Developing and qualifying UHPLC and gel/capillary electrophoresis methods for stability, lot release, and characterization testing.
2. Evaluating novel analytical techniques for platform development.
3. Contributing to method transfer to CDMOs.
4. Designing and conducting experimental investigations with guidance.
5. Preparing and reviewing study protocols and reports.

Additional Responsibilities:

• Planning experiments and adhering to deadlines.
• Sharing technical knowledge and skills with colleagues.
• Maintaining accurate laboratory records.
• Training on technical instruments and using equipment appropriately.
• Communicating research findings effectively.
• Following safety policies in laboratories.

Person Specification

Experience & Knowledge (Essential):

• At least 2 years of industry experience in recombinant protein or antibody/biopharmaceutical analytical development or QC.
• Hands-on expertise with HPLC/UHPLC techniques for protein analysis.
• Experience with electrophoretic methods such as CE-SDS.
• Knowledge of assay qualification/validation and GMP principles.
• Strong record-keeping and self-learning abilities.

Desirable:

• Experience with imaging capillary IEF, Western blotting, mass spectrometry.
• Understanding of stability studies and method transfer.
• Experience presenting scientific results.

Education & Qualifications:

• Essential: BSc or MSc in biochemistry, biotechnology, or related discipline.
• Desirable: PhD in a related discipline.