Scientist 2 - Synthetic and Mammalian Upstream

Centre for Process Innovation Limited; Tees Valley; On-site; GBP 80,000 - 100,000; Full time

Job summary

A leading innovation organization based in Tees Valley is seeking an Upstream Scientist 2 to join their Synthetic and Mammalian Upstream team. The role involves developing and optimizing processes for biologics production. Candidates should have practical mammalian cell culture experience and be prepared to work collaboratively across projects. Benefits include up to 36 days of holiday and life assurance.

Benefits

Up to 36 days holiday, including bank holidays

Life assurance and accident insurance schemes

Qualifications

• Practical experience in mammalian cell culture.
• Experience in setting up and running bioreactors.
• Knowledge of molecular, cellular, and vector biology.

Responsibilities

• Develop and optimize cell culture processes.
• Execute experimental/pilot scale runs and analyze results.
• Present experimental conclusions for internal review.

Skills

Cell culture

Problem solving

Bioreactor operation

Collaboration

Education

HNC or Foundation degree in a Scientific or Engineering discipline

Job description

Scientist 2 —Synthetic and Mammalian Upstream

CPI helps make great ideas and inventions areality. We’re ateam of intelligent people using advances in science and technology to solve the biggest global challenges in healthcare and sustainability.

Through our incredible people and innovation infrastructure, we collaborate with our partners in industry, academia, government, and the investment community to accelerate the development and commercialisation of innovative products.

From health technologies and pharmaceuticals to sustainable food and materials innovations, we turn the entrepreneurial spirit and radical thinking of our people and partners into incredible impact that makes our world abetter place.

Why this role is important for CPI’swork

CPI is recruiting for an Upstream Scientist 2 to join the established and growing Synthetic and Mammalian Upstream team, based at the Nigel Perry Building in Darlington. The team of high-performing Scientists are part of CPI ’s Biologics Technology Area. The team play akey role in delivering awide range of exciting projects focused on the development and optimisation of processes for the production of biologics including viral vectors, mAbs, RNA therapeutics and recombinant proteins.

In your role as aScientist 2 , you will use your experience and interest in upstream processing to support the delivery of innovative projects using different cell types (e.g. CHO , HEK 293 , MDCK , MSCs and IPSC ) to produce biological products such as recombinant proteins, antibodies, exosomes and viral vectors. The role will involve developing, optimising and scaling up cell culture processes using suspension, adherent and/or continuous cultures. As well as biological therapeutics, CPI is also involved in the development of cellular meat products, owing to its expertise and state of the art facilities to develop the technology and accelerate its path to market. You will be part of ateam that generates innovative solutions to problems and will work in adynamic and fast-moving environment across awide range of projects.

The Upstream Scientist we are recruiting will quickly adapt to the different aspects of the role and enjoy working in adynamic and collaborative environment on arange of projects. Pre-existing cell culture experience and experience in solving technical challenges and leveraging input from senior colleagues are essential to be successful in this role. Candidates will be committed to and will actively seek opportunities to develop themselves within this new and excitingrole.

Some exciting opportunities that the team have recently worked onare:

Key tasks in the role will include (but are not limited to ) the below ) , please download the job description for full details available on the CPI careers page :

• To keep up to date with developments in areas relevant to the role, and/or legislative and SHE-related changes as communicated by senior colleagues, ensuring understanding of these and any associated new best practices, methods or techniques.
• To set up, plan and execute experimental / pilot scale runs and analyse, interpret and report the results of these within agreed timescales and standards and in accordance with project requirements.
• To present and formally report experimental conclusions and supporting data for internal peer review and submission to clients, to agreed timescales and standards.
• To be responsible for providing clearly documented records of technical data, decisions, methodologies, calculations and software use in an agreed format.
• To take ownership in agreeing weekly workplans with line manager, project manager(s) and other relevant stakeholders, and delivering plan to agreed schedule.

The person we are seeking

Candidates are required to be educated to aminimum of HNC or Foundation degree (or equivalent) level in aScientific or Engineering discipline plus relevant industrial experience. It is essential that you are able to exhibit the professional mastery of principles and practices of molecular, cellular and vector biology, and upstream science gained in academic or industrial environments. The successful candidate will have practical mammalian cell culture experience and experience setting up and running bioreactors.

What does CPI offeryou?

At CPI , we offer awide range of benefits to our employees, this includes:

• Up to 36 days holiday, including bank holidays – Plus aholiday purchasing scheme
• Life assurance and accident insurance schemes

CPI is an organisation based in the UK . Commencement of employment is conditional to demonstrating right to work in the UK , sponsorship may be available.