Research Technician (UCL)

UK Dementia Research Institute; United Kingdom; On-site; GBP 30,000 - 40,000; Full time

Job summary

A leading research institute in the UK seeks a Research Technician to support a project on synucleinopathies related to Parkinson’s Disease. The role involves in vivo experimental work and biochemical analysis, requiring an Honours degree in a relevant field and experience with iPSC culture. This position is full-time, funded for one year, with excellent benefits including extensive holiday and a pension scheme.

Benefits

41 days holiday

Pension scheme

Cycle to work scheme

On-site gym

Enhanced maternity, paternity and adoption pay

Qualifications

• Experience with iPSC culture and neuronal differentiation.
• Understanding of neurodegeneration and synucleinopathies.
• Knowledge of biochemical analysis techniques.

Responsibilities

• Provide technical assistance with in vivo experimental work.
• Conduct histopathology techniques and biochemical analysis.
• Contribute to a project involving advanced murine models.

Skills

iPSC culture

Neuronal differentiation

Biochemical analysis

Western Blot

ELISA

Histopathology techniques

Education

Honours degree in Biophysics, Biochemistry, Molecular Biology or related discipline

Tools

Histology assays

Job description

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Organisation/Company UK Dementia Research Institute Research Field Neurosciences Researcher Profile Other Profession Positions Other Positions Country United Kingdom Application Deadline 17 Aug 2025 - 23:59 (Europe/London) Type of Contract Temporary Job Status Full-time Hours Per Week 36.5 Offer Starting Date 15 Sep 2025 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Reference Number B02-09170 Is the Job related to staff position within a Research Infrastructure? No

Offer Description

The UK Dementia Research Institute (UK DRI) is the biggest UK initiative supporting research to fill the major knowledge gap in our basic understanding of the diseases that cause dementia.

Research from UK DRI at UCL covers the journey from the patient to the laboratory and back to the patient with improved diagnosis, biomarkers and candidate therapies put to the test.

The Bartels Lab at the UK DRI at UCL specializes in the study of synuclein multimers and lipidomics in the context of Parkinson’s disease (PD). The lab plays a unique role in this field, addressing key research gaps through close collaborations with the National Hospital for Neurology and Neurosurgery and the Queen Square Brain Bank.

Dr Tim Bartels first discovered disease resistant forms of the α-synuclein protein and their destabilization in Parkinson’s Disease. His lab is interested in identifying the different factors that destabilize α-synuclein and that lead to neurotoxicity.

About the role

We are seeking a Research Technician to contribute to a project involving advanced murine models of synucleinopathies, especially the gut-brain axis in Parkinson’s Disease.

You will provide technical assistance with in vivo experimental work, histopathology techniques, biochemical analysis such as Western Blot and ELISA.

The post is available from 01 October 2025 and is funded by UK DRI at UCL for one year in the first instance.

You will have an Honours degree (minimum 2:1) or equivalent in Biophysics, Biochemistry, Molecular Biology or a related discipline, and experience with iPSC culture and neuronal differentiation. A background and knowledge in one or more of the following is essential: Neurodegeneration, synucleinopathies, biochemical analysis, such as detergent extraction and Western Blot, IHC. Experience of working with Biophysics, Biochemistry, Molecular Biology, Histology assays is also a requirement, as is an understanding of the mission of the UK DRI, an interest in its research work and a commitment to supporting high quality research.

Additional Information

As well as the exciting opportunities this role presents, we also offer great benefits, some of which are below:

• 41 Days holiday (27 days annual leave 8 bank holiday and 6 closure days)
• Additional 5 days’ annual leave purchase scheme
• Defined benefit career average revalued earnings pension scheme (CARE)
• Cycle to work scheme and season ticket loan
• On-site gym
• Enhanced maternity, paternity and adoption pay
• Employee assistance programme: Staff Support Service

We will consider applications to work on a part-time, flexible, and job share basis wherever possible.