Research Fellow in Thymus Transplantation

Great Ormond Street Hospital; London; On-site; GBP 35,000 - 45,000; Full time

Job summary

Great Ormond Street Hospital seeks a Research Fellow for its Thymus Transplantation research programme. The successful applicant will engage in groundbreaking research aimed at improving outcomes for children with congenital athymia, requiring a PhD and relevant laboratory experience. The role offers an inclusive work environment and opportunities for personal and professional growth.

Benefits

Flexible working

Help with childcare and travel

Excellent training and development opportunities

Qualifications

• Laboratory experience in culture and manipulation of cell lines.
• Experience in data/statistical analysis.
• Experience in bioinformatics.

Responsibilities

• Working closely with the Thymus Transplantation team on induced pluripotent stem cells.
• Supervising junior research staff and managing laboratory organization.
• Participating in translational research and departmental meetings.

Skills

Labouratory experience in culture and manipulation of cell lines

Effective communication and interpersonal skills

Organizational skills

Attention to detail

Education

PhD in a relevant field (Cellular and/or Molecular Biology)

Job description

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Research Fellow in Thymus Transplantation, London

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Client:

Great Ormond Street Hospital

Location:

London, United Kingdom

Job Category:

Other

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EU work permit required:

Yes

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Job Reference:

d66591fc235e

Job Views:

4

Posted:

02.06.2025

Expiry Date:

17.07.2025

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Job Description:

Job overview

We are looking for an energetic and enthusiastic post-doctoral researcher to work in the thymus transplantation research programme at Great Ormond Street Hospital and UCL Great Ormond Street Institute of Child Health. We are one of only two centres in the world treating children with thymus transplantation and the successful applicant will be part of a growing team focused on exciting translational research, with the ultimate aim of improving the outcomes for children with congenital athymia.

Based in central London, GOSH offers flexible working, help with childcare and travel, excellent training and development opportunities and assistance with finding somewhere to live.

For further information please contact Prof Graham Davies, Consultant Immunologist at , or Dr Austen Worth, Consultant Immunologist at

Main duties of the job

As the research fellow you will be working closely with the Thymus Transplantation team and taking a major role in the programme of work involving the generation of induced pluripotent stem cells and thymic epithelial precursors from patients’ fibroblasts as a means of investigating novel defects of thymic epithelial cell development, as well as the use of thymic organoid cultures for further disease modelling. There will be opportunity for the postholder to develop their own project within the overall umbrella of this work. You will undertake some supervision of more junior research staff involved in the manipulation of preparatory thymus culture conditions and assist in the running and organisation of the research laboratories.

The Thymus Transplantation team work alongside internationally recognised academics delivering cutting-edge translational research. There is a vibrant academic environment and post-holder will be participating in group and departmental meetings.

This opportunity is open to candidates with PhD in a relevant field (Cellular and/or Molecular Biology) with laboratory experience in culture and manipulation of cell lines and using molecular biological techniques.

Working for our organisation

GOSH is committed to recruiting the best person for the job, based solely on their ability and individual merit as measured against the criteria for the role; through a process that is fair, open, consistent and free from bias and discrimination.

We are committed to being a diverse and inclusive employer and foster a culture where all staff are valued, respected and acknowledged. All applicants will receive consideration for employment without regard to race, colour, national origin, religion, sexual orientation, gender, gender identity, age, disability status or length of time spent unemployed.

We particularly welcome applications from BAME communities, people with disabilities and/or long-term health conditions and LGBT+ community members.

We have policies and procedures in place to ensure that all applicants and employees are treated fairly and consistently. We are proud to be accredited as a Disability Confident Employer, a member of Business Disability Forum and a Stonewall Diversity Champion.

We have active and Executive supported BAME, LGBT+ and Allies, Disability and Long-Term Health Conditions and Women’s staff networks. Staff networks are employee-led groups formed around interests, issues and a common bond or background. Staff network members create a positive and inclusive work environment at Great Ormond Street Hospital by actively contributing to the Trust’s mission, values and efforts specific to inclusion. All of our staff networks are open to any employee.

Detailed job description and main responsibilities

The full job description provides an overview of the key tasks and responsibilities of the role, and the person specification outlines the qualifications, skills, experience, and knowledge required. For both documents please view the attachment/s below.

Person specification

GOSH Culture and Values

• Our Always values
• Experience of working as part of a diverse team.
• Experience of contributing to an inclusive workplace culture.
• Commitment to a policy of equal opportunity and the ability to work harmoniously with colleagues and students of all cultures and backgrounds
• PhD in a relevant field (Cellular and/or Molecular Biology)

Experience/Knowledge

• Laboratory experience in culture and manipulation of cell lines
• Laboratory experience of using molecular biological techniques
• Experience in data/statistical analysis
• Experience of culture and manipulation of primary human cell cultures
• Experience in bioinformatics

Skills/Abilities

• Effective spoken and written English and good communication and interpersonal skills
• Excellent organizational skills
• Commitment to high quality research and attention to detail