Research Fellow in Lung Remodelling

Cyber Security Academy Southampton; Southampton; On-site; GBP 40,000 - 55,000; Full time

Job summary

University of Southampton is recruiting a Research Fellow in the Lung Resilience and Remodelling group. The role, based at University Hospital Southampton, involves working with human lung tissue and BAL analyses, 3D cell culture, and molecular techniques. A PhD in cell and molecular biology and strong English communication are essential.

The appointment is full-time and fixed-term until 31 March 2027. Applicants with experience in primary lung cell culture, 3D culture, and immunohistochemistry

Qualifications

• Essential: PhD in cell and molecular biology with experience in cell culture and at least some listed techniques.
• Desirable: experience with primary lung cell culture, 3D culture techniques and immunohistochemistry.
• Ability to collaborate effectively in a translational research team and work across laboratories.

Responsibilities

• Perform analyses on human lung tissue and bronchoalveolar lavage samples.
• Conduct 3D cell culture using primary cells and established lines.
• Analyse cellular responses with ELISA and RT-qPCR and manipulate cells pharmacologically or by gene editing.
• Adapt techniques across multiple laboratories with initiative and reliability.

Skills

Cell culture

Molecular biology

ELISA

RT-qPCR

3D cell culture

Education

PhD in cell and molecular biology

Job description

We are seeking to recruit a Research Fellow in the Faculty of Medicine at the University of Southampton within the Lung Resilience and Remodelling group led by Professor Mark Jones

Working as part of a dynamic translational research team consisting of basic and clinical scientists within the NIHR Southampton Biomedical Research Centre, the successful candidate will be based in the Brooke Laboratory at University Hospital Southampton.

The role will involve human lung tissue and bronchoalveolar lavage analyses, 3D cell culture (including primary cells), analysis of cell responses by molecular and cellular techniques including ELISA, RT-qPCR, and manipulation of cells by pharmacological and gene knock-out/knock-in techniques.

For this position, you must have a PhD or equivalent professional qualifications and experience in cell and molecular biology. Experience of cell culture and at least some of the techniques listed above is essential, while experience in primary lung cell culture, 3D culture techniques, and (immuno)histochemistry is desirable.

The ideal candidate will be able to adapt to working with a variety of techniques across different laboratories, working efficiently and diligently, with a strong work ethic and able to use its own initiative. They will be team-oriented, with excellent organisational skills, and reliable. The successful applicant must have excellent spoken and written English communication skills.

This is a full time fixed term role until 31 st March 2027.

For informal enquiries, please contact Professor Mark Jones - [e-mail]

Applications for Research Fellow positions will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification.

As a university we aim to create an environment where everyone can thrive and are proactive in fostering a culture of inclusion, respect and equality of opportunity. We believe that we can only truly meet our objectives if we are reflective of society, so we are passionate about creating a working environment in which you are free to bring your whole self to work. With a generous holiday allowance as well as additional university closure days we are committed to supporting our staff and students and open to a flexible working approach.

For assistance contact Recruitment on [phone] or [e-mail] quoting the job number.