Research Fellow in Impact of Fluid-Induced Forces on Protein Stability

University of Leeds; Leeds; On-site; GBP 35,000 - 55,000; Full time

Job summary

An established research-intensive university is seeking a Fluid Mechanics Researcher to contribute to groundbreaking biopharmaceutical projects. This role involves developing innovative fluid-based devices and collaborating with leading industrial partners to enhance protein stability and manufacturability. The successful candidate will work in a supportive environment that promotes research career advancement, offering flexible working arrangements and numerous personal development opportunities. Join a team committed to pushing the boundaries of biopharmaceutical research and making a significant impact in the field.

Benefits

42 days of annual leave

Generous pension scheme

Health and Wellbeing benefits

Discounted gym memberships

Personal development opportunities

On-site childcare

Shopping discounts

Travel schemes

Qualifications

• Experience in developing small-scale fluid-based devices.
• Proven track record in assessing protein stability.

Responsibilities

• Develop innovative approaches for stressing and evaluating protein responses.
• Collaborate with scientists to analyze protein behavior.

Skills

Fluid Mechanics

Fluid-Flow Equipment Design

Micro-Fluidic Systems

Measurement Techniques

Education

PhD in Engineering or Biology

Master's in a related field

Job description

Job Opportunity: Fluid Mechanics Researcher in Biopharmaceuticals

We are seeking a researcher with experience in developing and quantifying small-scale fluid-based devices to support the development of next-generation protein-based medicines. This multidisciplinary project, spanning engineering and biology, is based at one of the UK's leading research-intensive universities.

This position is part of the EPSRC-funded project titled EMBeDs: Ensuring Manufacturability of next-generation Biopharmaceuticals by Design. The project involves collaboration with industrial partners AstraZeneca and UCB, focusing on creating robust, effective protein candidates capable of withstanding manufacturing processes.

Our team has a proven track record in developing novel devices to assess protein stability under hydrodynamic forces and in devising unique measurement techniques for candidate molecules. The work will focus on developing new methods to stress proteins in a controlled manner.

Key responsibilities include applying your expertise in fluid mechanics and fluid-flow equipment design to develop innovative approaches for stressing and evaluating protein responses. Experience with micro- and milli-fluidic systems is essential, as samples are limited. You will collaborate with scientists to select physics-based measurement techniques and analyze protein behavior, presenting findings to industrial partners and preparing publications.

We offer flexible working arrangements and a supportive environment for your research career advancement.

How to Apply and Contact

For further information or queries, please contact:

• Professor Nikil Kapur, Professor of Applied Fluid Mechanics
• Tel: [phone]
• Email: [e-mail]

This position may be eligible for sponsorship under the Skilled Worker visa route; first-time applicants should review salary requirements. For research roles, eligibility under the Global Talent visa will also be considered.

What We Offer

• 42 days of annual leave (including holidays and university closure days)
• Generous pension scheme with 14.5% employer contribution
• Health and Wellbeing benefits, including discounted gym memberships
• Personal development opportunities through courses and training
• Additional benefits such as on-site childcare, shopping discounts, and travel schemes