Research Fellow in Host Pathogen Interactions

Leeds; Leeds; Hybrid; GBP 42,000 - 52,000; Full time

Benefits offered by this job

26 days holiday + bank holidays

Gym & wellbeing discounts

Personal development courses

On-site childcare

Travel schemes

Job summary

University of Leeds invites applications for a Research Fellow to explore host-pathogen interactions in bunyaviruses. The role involves genome-wide screening, genome editing, and advanced cell imaging to define host factors and viral replication mechanisms.

The successful candidate will collaborate across virology, immunology, and imaging groups, with access to state-of-the-art facilities and a strong publication track record expected.

Qualifications

• PhD with postdoctoral experience in host-pathogen interactions and genome-wide screening.
• Proven publication record in high-ranking journals.

Responsibilities

• Study bunyavirus host–pathogen interactions at molecular/atomic level.
• Implement genome-wide CRISPR-Cas9 and haploid cell screening.
• Dissect mechanisms via imaging and functional manipulation.

Skills

Host-pathogen interactions

Imaging techniques

Scientific publishing

Education

PhD in host-pathogen interactions

Tools

CRISPR-Cas9

Genome-wide screening

Proteomics

Job description

Research Fellow in Host Pathogen Interactions

Research Fellow in Host Pathogen Interactions

Are you an ambitious researcher looking for your next challenge? Do you have an established background in host pathogen interactions and genomic screening? Do you want to further your career in one of the UKs leading research intensive Universities?

We have a vacancy for a molecular and cell biologist to study the host-pathogen interactions of a group of viruses known as the bunyaviruses. This appointment is part of an international collaboration involving scientists working in virology, immunology, structural biology, and cutting-edge image analysis. We seek to understand the formation of viral factories by bunyaviruses within host cells at the molecular and atomic level. One specific goal of the project will be to use genome-wide screening and proteomic approaches to define host restriction factors and molecular components essential for the viral life cycle. The work will involve the implementation of genome-wide CRISPR-Cas9, and haploid cell screening followed by mechanistic dissection via imaging and functional manipulation.

You should have a PhD and post doctorial experience, in host pathogen-interactions, genome-wide screening, molecular biology and cell imaging techniques, as well as a proven publication record in high-ranking journals. The successful candidate will join the thriving research environment within the Faculty of Health and Life Sciences, and have the opportunity to use and gain experience of new state-of-the-art research facilities in cell biology, molecular virology and cell imaging.

What we offer in return

• 26 days holiday plus approx.16 Bank Holidays/days that the University is closed by custom (including Christmas) – That’s 42 days a year!
• Health and Wellbeing: Discounted staff membership options at The Edge, our state-of-the-art Campus gym, with a pool, sauna, climbing wall, cycle circuit, and sports halls.
• Personal Development: Access to courses run by our Organisational Development & Professional Learning team.
• Access to on-site childcare, shopping discounts and travel schemes are also available.

And much more!