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An innovative research opportunity awaits a postdoctoral fellow in London, focusing on biomedical devices for ALS and FTD research. This role involves designing and fabricating cutting-edge neuromuscular junction models and collaborating with multidisciplinary teams to explore neurodegenerative diseases. The ideal candidate will possess a PhD in a relevant field and have expertise in polymer science and tissue engineering. Join a dynamic environment where your contributions will help pave the way for novel therapeutic targets. With generous holiday allowances and excellent benefits, this position is perfect for those passionate about making a difference in biomedical research.
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London, United Kingdom
Other
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Yes
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41ac9ae1a3c3
7
26.04.2025
10.06.2025
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About the role
Applications are invited for a postdoctoral research fellow to join the Song laboratory (This is a new exciting role funded by a multi-center 5-year MRC and MNDA programme grant to discern the effects of Amyotrophic lateral sclerosis (ALS)/Fronto-temporal dementia (FTD) mutations on human neuron intrinsic and synaptic properties as well as neural network function.
The successful candidate will design and fabricate neuromuscular junction model devices, and work together with multi-disciplinary teams to tackle the mechanism of ALS/FTD neurodegenerative diseases.
This role is for a qualified and experienced scientist/engineer who has been working in an academic or commercial research laboratory/company related to biomedical devices for muscle/neuron sensing, neuromuscular junction, neuron/muscle tissue/disease modelling and drug discovery. We design and fabricate synthetic scaffolds, biosensors and integrate with a human iPSC-based neuromuscular co-culture system and apply this system to investigate the cause of human ALS/FTD conditions, and lead to novel therapeutic targets.
The post holder will contribute to the plan to deliver technical innovation and lead specified work packages of developing human iPSC-based neuromuscular junction model systems and ALS/FTD disease models in collaboration with other teams at UCL and KCL. To ensure successful development of the cellular model device and facilitate multidisciplinary collaborators to progress towards understanding the cause of ALS/FTD conditions, the candidate requires a strong background/knowledge of design, fabrication and integration of polymeric nanofiber-based devices, muscle/neuronal cell-culture devices and muscle/neuron detectors. Experience in polymer synthesis and process, electrospinning technique, neuron/muscle tissue engineering, cell culture and characterization is also desirable. In addition, they also require excellent interpersonal skills to work within and across diverse and interdisciplinary teams.
About you
The post holder will have the following:
What we offer
As well as the exciting opportunities this role presents, we also offer some great benefits some of which are below:
The full range of staff benefits can be found