Research Associate (Narita Group) (Fixed Term)

University of Cambridge; Cambridge; On-site; GBP 36,000 - 45,000; Full time

Job summary

Join a world-leading research institute as a Postdoctoral Research Associate focusing on oncogene-induced senescence and liver cancer. You will engage in cutting-edge projects at the CRUK Cambridge Institute, collaborating across disciplines to advance cancer research. This exciting role requires a strong commitment to innovation and teamwork.

Qualifications

• Experience in cancer research using mouse models and human tissues is advantageous.
• Liver-focused experience helpful but not essential.
• Good communication skills and ability to work in a multidisciplinary team.

Responsibilities

• Contribute to research on early detection and prevention of primary liver cancer.
• Investigate oncogene-induced senescence (OIS) heterogeneity in mouse models.
• Explore gene regulation at a single-cell level.

Skills

Immune phenotyping

Flow cytometry

Mouse genetics

Immunohistochemistry

(Spatial) single-cell gene expression profiling

Education

PhD in a relevant field

Job description

Join us at the world-leading CRUK Cambridge Institute! We are a unique department of the University of Cambridge, core-funded by Cancer Research UK's charitable activities. The Narita Laboratory ( https://www.naritalab.com/ ) seeks a skilled Postdoctoral Research Associate for a 3-year fixed-term role.

This project investigates oncogene-induced senescence (OIS) heterogeneity and tumour initiation in mouse livers. We explore gene regulation at a single-cell level and how OIS and tumour-initiating cells impact immune responses (see e.g., Nature 2024 PMID 39112713, Genes Dev. 2025 PMID 40324881)

The successful candidate will contribute to cutting-edge research on the early detection and prevention of primary liver cancer using mouse models and human tissues. Experience in immune phenotyping, flow cytometry, mouse genetics, immunohistochemistry, and (spatial) single-cell gene expression profiling would be advantageous. A liver-focused experience would also be helpful, but not essential.

Applicants must hold or about to receive a PhD in a relevant field.

The ideal candidate will have the capacity for innovation, initiative, and creativity to solve mechanistic biological problems. We value good communication skills and the ability to work well in a multidisciplinary team.

This position is offered at Grade 7 on the university scale. Interviews are expected to take place in August 2025.

Fixed-term: The funds for this post are available for 3 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a security check.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

For more information about our research please see: https://www.cruk.cam.ac.uk/research-groups/narita-group/

Informal enquiries may be made to Julie Downer ( [e-mail] )

Please quote reference SW46601 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
Further information

• Research Associate SW46601 Further Particulars