Research Associate – Molecular Virology & Host Factors

Imperial College London; Greater London; On-site; GBP 42,000 - 54,000; Full time

Benefits offered by this job

41 days off per year

Generous pension schemes

Career progression opportunities

Job summary

Imperial College London seeks a Research Associate in Molecular Virology to study how viruses cross species barriers, focusing on early replication events inside mammalian cells. You will validate host factors linked to influenza A polymerase, performing genetic manipulations and integrating bioinformatics analyses.

The role involves work with diverse team, opportunities at a world-leading institution, and a sector-leading remuneration package including generous pension schemes and ample leave.

Qualifications

• Experience with mammalian cell systems and virology methods.
• Proficiency in genetic manipulation and data analysis.
• Familiarity with AlphaFold and bioinformatics approaches.

Responsibilities

• Validate host factor roles in influenza A polymerase within host cells.
• Knock down expression of candidate factors and measure virus replication.
• Assess colocalization of host factors with viral polymerase in situ.
• Compare interactions of host factors with viral RNPs from different RNA strands.

Skills

CRISPR

Cell culture

AlphaFold

Bioinformatics

Virus assays

Tools

Bioinformatics tools

Data analysis pipelines

Job description

Imperial College London seeks a Research Associate in Molecular Virology to study how viruses cross species barriers, focusing on early replication events inside mammalian cells. You will validate host factors linked to influenza A polymerase, performing genetic manipulations and integrating bioinformatics analyses.

The role involves work with diverse team, opportunities at a world-leading institution, and a sector-leading remuneration package including generous pension schemes and ample leave.