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The University of Manchester seeks a Research Associate in Neuroscience to develop genetic therapies for epilepsy, focusing on microRNAs and their therapeutic effects. The ideal candidate will possess strong skills in electrophysiology and gene expression analysis, with opportunities for hybrid working arrangements.
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We are seeking a Postdoctoral Research Associate to develop preclinical genetic therapies for epilepsy.
The project focuses on microRNAs – short noncoding RNAs which negatively regulate gene expression – and their role(s) in epilepsy. The candidate will use a combination of cell culture and rodent models to interrogate the mechanistic and therapeutic effects of novel microRNA-based therapies. In particular, we will focus on the relationships between microRNA and GABAergic signalling in the context of epilepsy.
The ideal candidate will have strong experience in patch clamp electrophysiology and gene expression analysis with RT-qPCR. Candidates will ideally have experience of working with laboratory rodents, as well as in vitro/in vivo epilepsy models and rodent behavioural assays. Candidates with experience in most (but perhaps not all) of these approaches are encouraged to enquire or apply.
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