Research Associate in Neuroscience

The University of Manchester; Manchester; Hybrid; GBP 30,000 - 40,000; Full time

Job summary

A leading university is seeking a Postdoctoral Research Associate to develop innovative preclinical genetic therapies for epilepsy. The successful candidate will focus on the role of microRNAs and utilize advanced techniques including patch clamp electrophysiology and gene expression analysis. This position offers a competitive package and encourages applications from candidates with diverse backgrounds.

Benefits

Fantastic market leading Pension scheme

Excellent employee health and wellbeing services

Exceptional starting annual leave entitlement

Additional paid closure over Christmas

Local and national discounts at major retailers

Qualifications

• Strong experience in patch clamp electrophysiology and gene expression analysis with RT-qPCR.
• Experience with laboratory rodents and in vitro/in vivo epilepsy models is preferred.
• Candidates with various levels of experience in these approaches are encouraged to apply.

Responsibilities

• Develop preclinical genetic therapies for epilepsy using microRNA-based therapies.
• Interrogate the effects of microRNAs on GABAergic signalling in epilepsy.
• Utilize cell culture and rodent models for research purposes.

Skills

Patch clamp electrophysiology

Gene expression analysis

Working with laboratory rodents

Job description

We are seeking a Postdoctoral Research Associate to develop preclinical genetic therapies for epilepsy.

The project focuses on microRNAs - short noncoding RNAs which negatively regulate gene expression - and their role(s) in epilepsy. The candidate will use a combination of cell culture and rodent models to interrogate the mechanistic and therapeutic effects of novel microRNA-based therapies. In particular, we will focus on the relationships between microRNA and GABAergic signalling in the context of epilepsy.

The ideal candidate will have strong experience in patch clamp electrophysiology and gene expression analysis with RT-qPCR. Candidates will ideally have experience of working with laboratory rodents, as well as in vitro/in vivo epilepsy models and rodent behavioural assays. Candidates with experience in most (but perhaps not all) of these approaches are encouraged to enquire or apply.

What you will get in return:

• Fantastic market leading Pension scheme
• Excellent employee health and wellbeing services including an Employee Assistance Programme
• Exceptional starting annual leave entitlement, plus bank holidays
• Additional paid closure over the Christmas period
• Local and national discounts at a range of major retailers

As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.

Our University is positive about flexible working - you can find out more here

Hybrid working arrangements may be considered.

Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies.

Any recruitment enquiries from recruitment agencies should be directed to [e-mail] .

Any CV's submitted by a recruitment agency will be considered a gift.

Enquiries about the vacancy, shortlisting and interviews:

Name: Dr Gareth Morris.

Email [e-mail]

Lab website : www.morrisepilepsylab.com

General enquiries:

Email: [e-mail]

Technical support:

https://jobseekersupport.jobtrain.co.uk/support/home

This vacancy will close for applications at midnight on the closing date.

Please see the link below for the Further Particulars document which contains the person specification criteria.