Research Associate in Chemistry University of York York, United Kingdom

University of York; York; On-site; GBP 60,000 - 80,000; Full time

Job summary

A prominent educational institution in York is seeking a researcher to develop a programmable multienzyme assembly for enzymatic nucleic acid synthesis. The role requires a PhD in biochemistry or related fields, with a focus on enzyme engineering and collaborative research approaches. Candidates should demonstrate excellent communication skills and a commitment to diversity and inclusivity.

Qualifications

• PhD or equivalent experience required.
• Hands-on experience in protein/peptide library design and analysis.
• Excellent scientific communication skills.

Responsibilities

• Develop a programmable multienzyme assembly for nucleic acid synthesis.
• Apply multidisciplinary approaches including enzyme kinetics and AFM.

Skills

Replication/transcription biochemistry

Protein library design

Collaborative work

Scientific communication

Education

PhD in biochemistry, bioengineering, or structural biology

Job description

Overview

You will be involved in developing a programmable multienzyme assembly for enzymatic nucleic acid synthesis characterised using a multidisciplinary approach including protein library design, single-molecule FRET (smFRET), mass spectrometry, enzyme kinetics and atomic force microscopy (AFM). Knowledge of nucleic acid-modifying enzymes, specifically DNA/RNA polymerases, and enzymatic protein assemblies is essential.

Qualifications

• A PhD in biochemistry, bioengineering, structural biology or equivalent experience
• Excellent knowledge in replication/transcription biochemistry to engage in high-quality research
• Enthusiasm for multidisciplinary research related to multienzyme systems, enzyme engineering and nucleic acids synthesis
• Collaborative ethos, positive attitude and committed to personal development
• Hands-on experience in designing, generating and analysing a protein/peptide library
• Excellent oral scientific communication skills and able to write up research work for publication
• Commitment to values of equality, diversity and inclusion