Research Associate in Chemical Biology - College of Engineering and Physical Sciences -104075 -[...]

TN United Kingdom; United Kingdom; On-site; GBP 60,000 - 80,000; Full time

Job summary

An established industry player is seeking a Research Associate in Chemical Biology to join their dynamic team. This role involves assisting in groundbreaking research aimed at developing innovative peptidomimetic inhibitors. You will collaborate closely with experienced researchers, conduct vital experiments, and contribute to the publication of findings in prestigious journals. If you are passionate about advancing scientific knowledge and have a strong background in chemical biology, this is an exciting opportunity to make a significant impact in the field. Join a supportive environment that values diversity and fosters professional growth.

Qualifications

• Masters level degree in chemical biology or relevant discipline required.
• Practical experience in cell culture and confocal microscopy is essential.

Responsibilities

• Assist in developing peptidomimetic inhibitors and running a research lab.
• Conduct experiments and support the dissemination of research results.

Skills

Cell culture

Confocal microscopy

Functional cell-based assays

Research writing

Team collaboration

Organizational skills

Time management

Education

Masters in Chemical Biology

Tools

Fluorescence anisotropy

Western Blot

Job description

Social network you want to login/join with:

Research Associate in Chemical Biology - College of Engineering and Physical Sciences -104075 - Grade 6

Client:

University of Birmingham

Location:

United Kingdom

Job Category:

Education

EU work permit required:

Yes

Job Reference:

2b9c3a6564cd

Job Views:

23

Posted:

21.03.2025

Expiry Date:

05.05.2025

Job Description:

Summary

The role has arisen as a consequence of the award of a BBSRC sLoLa award (SPIDR) to Prof Andrew Wilson (University of Birmingham). The purpose of the role is: (i) to assist Prof Wilson and Dr Chiara Arno in developing cell permeable peptidomimetic inhibitors of the interaction between the Aurora A kinase and its regulatory clients; (ii) to assist Professor Wilson in running and maintaining a research laboratory; (iii) to facilitate collaboration with wider members of the SPIDR team at the Universities of Leeds and Oxford. The role is available for 12 months.

Main Duties

• Work in close collaboration with a senior research associate in the Wilson group and as part of a larger team of researchers to design, plan and conduct a programme of investigation in consultation with Prof Andrew Wilson, using appropriate methods to analyse and interpret research data.
• Perform analyses of cell-uptake behaviour of peptidomimetic protein-protein interaction inhibitor candidates using confocal imaging, alongside functional assays (e.g., toxicity analyses).
• Support the acquisition of biochemical and biophysical assay data by performing protein expression and/or carrying out fluorescence anisotropy competition assays.
• Assist Prof Wilson in the dissemination of research results by contributing to publication in leading peer-reviewed journals and by presentation at national and international conferences.
• Support the running of the Wilson group’s research activities and communication through participation at group meetings/seminars, contributing to the supervision of junior researchers and PhD students, and acting as a mentor to less experienced colleagues.
• Support ongoing collaborations with relevant researcher groups including Richard Bayliss and Megan Wright (University of Leeds) and Fanni Gergely (University of Oxford).
• Contribute to and encourage a safe working environment.
• Promote equality and value diversity, acting as a role model and fostering an inclusive working culture.

Person Specification

• A masters level degree in chemical biology or relevant allied discipline.
• Practical experience of cell culture and confocal microscopy.
• Practical experience in functional cell-based assays (e.g., MTS, reporter gene, Western Blot).
• The ability to write up research independently, together with the ability to contribute to peer-reviewed publications in international journals.
• A proven ability to work under supervision and as part of a team, with a strong commitment to research in a team environment.
• Good organisational, time management, and planning skills, with the ability to meet tight deadlines, manage competing demands, and work effectively under pressure without close support.
• Ability to assess resource requirements, use resources effectively, and contribute to broader laboratory management.
• Knowledge of the protected characteristics of the Equality Act 2010, and how to actively ensure in day-to-day activity in own area that those with protected characteristics are treated equally and fairly.
• Experience in the analyses of cell-uptake of synthetic compounds and peptides.
• Practical experience of protein expression and purification.
• Experience of biophysical/biochemical assays to assess functional effects of inhibitor candidates.