Research Associate II, In Vivo

AskBio Inc.; City of Edinburgh; On-site; GBP 30,000 - 50,000; Full time

Job summary

An innovative clinical-stage gene therapy company is seeking a motivated individual to support downstream analysis of animal studies. This hands-on role involves performing molecular biology assays, immunohistochemistry protocols, and animal procedures. The ideal candidate will possess a Bachelor's degree in a relevant field, have experience in molecular biology techniques, and demonstrate strong organizational and presentation skills. Join a pioneering team dedicated to transforming lives through gene therapy and contribute to groundbreaking projects in a collaborative environment.

Qualifications

• 2+ years' experience in molecular biology and related techniques.
• Strong skills in histology and data presentation.

Responsibilities

• Perform molecular biology assays and immunohistochemical techniques.
• Conduct procedures on animals and analyze data.

Skills

Molecular Biology

Immunohistochemistry

Data Analysis

Rodent Handling

Organizational Skills

Presentation Skills

Education

Bachelor's degree in Biology

Bachelor's degree in Chemistry

Tools

qPCR

RT-PCR

DNA/RNA Extractions

Cryosectioning

Microscopy

Job description

Asklepios BioPharmaceutical, Inc. (AskBio) is a leading, clinical-stage gene therapy company founded in 2001 based on the work of adeno-associated virus (AAV) gene therapy visionary and pioneer, Jude Samulski, PhD. Since that time, our commitment to developing life-saving medicines that can potentially cure genetic diseases has never wavered.

At AskBio, we’ve built a foundation of therapeutic programs, AAV manufacturing and a rich portfolio of patented technology. Our therapeutic focus includes neuromuscular, central nervous system, cardiovascular and metabolic diseases with clinical trials underway for Pompe disease, Parkinson’s disease, and congestive heart failure. Our gene therapy platform includes Pro10, an industry-leading proprietary cell line manufacturing process, and an extensive AAV capsid and promoter library.

We became a wholly-owned, independently operated, subsidiary of Bayer AG in late 2020 as a cornerstone of its newly formed Cell & Gene Therapy (CGT) platform. Our global headquarters is in Research Triangle Park, NC. Additionally, we have significant operations in Philadelphia, PA, Columbus, OH, Scotland, France, Germany, and Spain.

Our vision: Pioneering science to create transformative molecular medicines.

Our mission: Lead innovative science and drive clinical outcomes to transform people's lives.

Our Principles

• Advance innovative science by pushing boundaries.
• Bring transformative therapeutics to patients in need.
• Provide an environment for employees to reach their fullest potential.

Our Values

• Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.
• Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view.
• Embrace Responsibility. We are humbled by the enormity of our mission. We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers.
• Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.
• Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through.

Position Summary
Reporting to the in vivo manager, you will provide support in running downstream analysis of animal studies on site. This is a hands-on role with significant responsibility, requiring performing molecular biology assays at high throughput, performing immunohistochemistry protocols, and conducting procedures on animals.

Job Responsibilities

• Perform molecular biology techniques such as qPCR, RT-PCR, DNA/RNA extractions and protein assays at high throughput.
• Perform immunohistochemical techniques such as tissue processing, sectioning, antibody staining and imaging.
• Perform procedures with animals, such as dosing and tissue dissections.
• Process, analyze, and present data.
• Deliver quality work within project timelines.
• Manage workload with minimal supervision.

Minimum Requirements

• Bachelor’s degree in biology, chemistry, or related field with 2+ years’ related experience.
• Motivated to learn and develop new techniques.
• Enthusiastic and positive attitude.
• Ability to present data confidently and clearly, both verbally and through written reports.
• Experience of working with rodents.
• Strong organizational and planning skills.
• Demonstratable skills in histology including cryosectioning and immunofluorescence.
• Demonstratable skills in molecular biology.

Preferred Skills & Abilities

• Experience in molecular biology, particularly qPCR, RT-PCR, DNA/RNA extractions.
• Experience of working with rodents, including RoAs: IV, PO, IP, SC, IM.
• Experience with cryosectioning, microtomy and immunohistochemical techniques.
• Experience in microscopy desirable but not essential.

Asklepios BioPharmaceutical, Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid job‐related requirements. If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at [phone] or sending us an email at [e-mail].
Agencies: Please do not contact any employee at AskBio about this requisition. Any resume submitted by a recruitment agency to any employee at AskBio, through any medium, will be deemed the sole property of AskBio unless the agency was engaged by AskBio Talent Acquisition team to recruit for that position. All agencies must have a prior executed service agreement with AskBio prior to any search engagement. If a candidate who was submitted outside of the AskBio agency process is hired by AskBio, no fee or payment of any kind will be paid to the agency.