Research Associate (Ali Group) (Fixed Term)

University of Cambridge; Cambridge; On-site; GBP 30,000 - 40,000; Full time

Job summary

The Ali group at a leading university seeks a Postdoctoral Research Associate to explore how breast tumour structures influence treatment responses. This role involves advanced tissue imaging and data analysis, contributing to innovative cancer research.

Qualifications

• Experience in medical oncology and precision medicine.
• Strong background in computational techniques for TME analysis.

Responsibilities

• Characterise regulators of immunosuppressive TME in breast cancer.
• Contribute to translational research on multicellular ecosystems.

Skills

Computational Experience

Biomedical Research

TME Analysis

Education

PhD in Biomedical Sciences

Job description

The Ali group invites applications for a Postdoctoral Research Associate. Our goal is to understand how the multicellular structure of breast tumours drives relapse and therapeutic response. We characterise the dynamic multicellular structure of human cancers using quantitative tissue imaging (imaging mass cytometry; spatial transcriptomics; digital pathology) and sophisticated image processing.

We are assembling tissue imaging datasets of unprecedented depth and size in both observational studies and clinical trials. This will enable us to unmask spatial phenotypic traits that emerge during disease progression and treatment, and to identify those that drive prognosis and therapeutic response. The main aim of this project is to characterise regulators of an immunosuppressive TME and their impact on immunotherapy response in breast cancer. To address this question reliably, we have generated a novel highly curated dataset using samples from a major breast cancer immunotherapy trial. The project would particularly appeal to biomedical researcher with computational experience in TME analysis, training in medical oncology and precision medicine looking to significantly build on their skills in a specialised lab.

As a member of our team, you would contribute to cutting-edge translational research designed to unravel the complex multicellular ecosystems that drive breast cancer and identify actionable pragmatic biomarkers.

Fixed-term: The funds for this post are available for 18 months in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check) check and a security check.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Please ensure that you upload a 2-page Curriculum Vitae (CV), a covering letter and publications list in the Upload section of the online application. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application.

Please quote reference SW45951 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
Further information

• Further Particulars (Research Associate)