Research Assistant in Organoid/iPSCs models

University of Oxford; Oxford; On-site; GBP 25,000 - 35,000; Full time

Job summary

A leading university seeks a highly motivated Research Assistant for a one-year fixed-term position in oncology research. The role focuses on advanced cancer research using the latest techniques including CRISPR and organoid models. Ideal candidates will have a degree in a related field and a strong interest in cancer biology.

Benefits

Excellent contributory pension scheme

38 days annual leave including bank holidays

Comprehensive childcare services

Family leave schemes

Cycle loan scheme

Discounted bus travel and Season Ticket loans

Membership to social and sports clubs

Qualifications

• Interest in epigenetics, cancer biology, and tumour microenvironment.
• Strong organizational skills and independence.
• Ability to work in a team.

Responsibilities

• Support research on RAS pathway activation in gene regulation and tumour development.
• Develop APC/KRAS mutant models via CRISPR and create co-culture systems.
• Receive training in organoid culturing, CRISPR editing, and genomics techniques.

Skills

Organizational skills

Independence

Teamwork abilities

Education

Undergraduate degree in genetics, biochemistry, molecular biology, or related field

Job description

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Research Assistant in Organoid/iPSCs models, Oxford

Client: University of Oxford

Location: Oxford, United Kingdom

Job Category: Other

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EU work permit required: Yes

Job Reference:

e9fe01a9fe22

Job Views:

8

Posted:

22.06.2025

Expiry Date:

06.08.2025

Job Description:

We are seeking a highly motivated Research Assistant to join Dr Giulia Orlando's research group in the Department of Oncology at the University of Oxford. This role supports research on RAS pathway activation in gene regulation and tumour development in colorectal cancer. The project employs advanced technologies such as bulk RNAseq, ATACseq, and 10X single-cell multiome, combined with 3D organoid models, iPSCs, and primary patient samples to identify new therapeutic targets. Responsibilities include developing APC/KRAS mutant models via CRISPR and creating co-culture systems to study epigenetic changes in the tumour microenvironment. You will receive training in organoid culturing, CRISPR editing, FACS, and genomics techniques, with opportunities for collaboration and scientific growth. This is a full-time, fixed-term position for 1 year.

About you: You will hold an undergraduate degree in genetics, biochemistry, molecular biology, or a related field, with a keen interest in epigenetics, cancer biology, and tumour microenvironment. Strong organizational skills, independence, and teamwork abilities are essential.

What We Offer: We prioritize employee wellbeing and offer benefits including:

• An excellent contributory pension scheme
• 38 days annual leave including bank holidays (pro-rata for part-time)
• Comprehensive childcare services
• Family leave schemes
• Cycle loan scheme
• Discounted bus travel and Season Ticket loans
• Membership to social and sports clubs

Application Process: Applications must be submitted online.