Research Assistant in Circadian and Sleep Neuroscience

University of Manchester; Manchester; Hybrid; GBP 10,000 - 40,000; Full time

Job summary

An exciting opportunity awaits within a leading research institution focused on circadian and sleep neuroscience. This role involves engaging in groundbreaking research to explore the interactions between light and circadian mechanisms in regulating sleep-wake cycles. You will be part of a vibrant neuroscience community, working with advanced methodologies in a collaborative environment. The position offers flexibility in start date and a commitment to professional development, making it ideal for those passionate about advancing their careers in life sciences. Join us in this impactful journey to uncover the mysteries of the brain and its rhythms.

Benefits

Market leading Pension scheme

Employee Assistance Programme

Exceptional annual leave entitlement

Paid closure over Christmas

Local and national retail discounts

Qualifications

• Experience in life sciences with a focus on neurophysiology is essential.
• Ability to work independently and conduct electrophysiological recordings.

Responsibilities

• Conduct innovative brain circuit manipulation and mapping.
• Perform physiological and behavioral measurements in rodent models.

Skills

Neurophysiology

Electrophysiological recording

Circadian rhythm studies

Independent working

Education

Degree in Life Sciences

Tools

Whole-cell patch clamp

Laboratory rodents

Job description

The Division of Neuroscience within the School of Biological Sciences, Faculty of Biology Medicine and Health wish to appoint a laboratory-based Research Assistant to an exciting project exploring how light and circadian mechanisms interact in the brain’s supraoptic nucleus to regulate daily rhythms and timing in the sleep and wake cycles. This BBSRC funded project offers a fantastic opportunity to be at the forefront of circadian and sleep neuroscience to understand how our sleep-wake cycles are regulated by light and circadian rhythm.

During this position, the post-holder will undertake a range of activities including the application of innovative approaches for brain circuit manipulation and mapping, in and ex vivo, with comprehensive physiological and behavioural measurements, both in mice and our powerful new day-active rodent model (Rhabdomys Pumillio). Collectively, we expect this exciting programme of work will drive a step-change in our understanding of the brain mechanisms responsible for daily and circadian control of the sleep-wake cycle and much-needed insights into how these mechanisms differ between nocturnal and diurnal mammals (like us).

The successful candidate will join a thriving neuroscience and circadian community. You will also benefit from regular interactions with members of the Time, Vision and Behaviour, an informal grouping of seven labs with common interests in light and circadian neuroscience, who share equipment and complementary skills, and the wider Centre for Biological Timing research community.

Start date is flexible, but we hope to have someone in post by March 2025, for a period of 36 months. Applicants are expected to have a good level of experience in a relevant branch of life sciences. Full training is available, however, the ability to work independently is essential, as is experience in and practical knowledge of neurophysiology. Experience with electrophysiological recording, preferably whole-cell patch clamp electrophysiology, and/or studies of visual or circadian function is highly desirable. Experience with laboratory rodents and relevant surgical procedures is also desirable.

Successful candidates may be subject to pre-employment screening carried out on our behalf by a third party. The offer of employment will be dependent on the successful candidate passing this screening.

What you will get in return:

• Fantastic market leading Pension scheme
• Excellent employee health and wellbeing services including an Employee Assistance Programme
• Exceptional starting annual leave entitlement, plus bank holidays
• Additional paid closure over the Christmas period
• Local and national discounts at a range of major retailers

As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.

Our University is positive about flexible working.

Hybrid working arrangements may be considered.

Enquiries about the vacancy, shortlisting and interviews:

Name: Dr Mino Belle

Email: [e-mail]

General enquiries:

Email: [e-mail]

This vacancy will close for applications at midnight on the closing date.

Please see the link below for the Further Particulars document which contains the person specification criteria.