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Newcastle University is seeking a Research Assistant/Associate in Statistical and Computational Genetics to develop and apply statistical analysis methods for multi-omics data related to liver disease. This role offers an exciting opportunity to contribute to clinically relevant research with strong translational potential, alongside excellent employee benefits.
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Join to apply for the Research Assistant/Associate in Statistical and Computational Genetics role at Newcastle University
Salary
Research Assistant: £32,546 to £34,132 per annum
Salary
Research Assistant: £32,546 to £34,132 per annum
Research Associate: £35,116 to £45,413 per annum
Newcastle University is a great place to work, with excellent benefits . We have a generous holiday package; plus the opportunity to buy more, great pension schemes and a number of health and wellbeing initiatives to support you.
Closing Date: 28 June 2025
The Role
This is an exciting opportunity for a methodologically-focussed researcher with strong computational/statistical skills to contribute to cutting-edge methods development in a clinically relevant research area with strong translational potential.
Your role will be to develop and apply advanced statistical analysis methods to multi-omics data (SNP genotypes, gene-expression, CpG methylation and serum proteomics) derived from patients with liver disease and healthy controls, to identify causal pathways in disease development/progression.
The project forms part of a Wellcome Investigator Award in Science awarded to Professor Heather Cordell. The overall goal of this research is to develop and apply advanced statistical methods to help elucidate the biological mechanisms and causal pathways underpinning the correlations seen between genotype and phenotype in complex genetic disorders, with specific emphasis on liver and kidney disease. This will allow us to better understand the biological processes leading to disease development, thus enabling the development of potential therapies and cures.
Identifying genes and their protein products which alter disease risk will point to potential new drug targets and allow opportunities for re-purposing of existing drugs. We will use measurements of genetic factors and potential intermediate processes such as gene expression, DNA methylation and protein levels, available through long-standing collaborations with clinical colleagues. A key goal of our research is to develop methods that integrate these different data types with one another, and with similar data from external sources.
This post is fixed term until 31st March 2027. You’ll be based in Newcastle Upon Tyne at the Centre for Life campus that has fantastic transport links, and we offer a hybrid and flexible working model.
For informal enquiries contact: Professor Heather Cordell heather.cordell@newcastle.ac.uk
Find out more about the Faculty of Medical Sciences, please click here .
Find out more about our Research Institutes, please click here .
To apply, please complete an online application and upload a plain text copy of your CV and covering letter only. In your covering letter, you should evidence how you meet or exceed the essential and desirable requirements for the role. Please note, any other ‘Additional Document’ you upload will not be received by the reviewing panel.
As part of our commitment to career development for research colleagues, the University has developed 3 levels of research role profiles . These profiles set out firstly the generic competences and responsibilities expected of role holders at each level and secondly the general qualifications and experiences needed for entry at a particular level.
Key Accountabilities
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