R&D Scientist I

ZipRecruiter; Malvern; On-site; GBP 72,000 - 76,000; Full time

Job summary

A leading company seeks an R&D Scientist II to support expert testing of CAR-T cell therapies in Malvern. This role emphasizes analytical development and method validation, crucial for advancing therapeutic treatments. Join a dedicated team driving innovation in biotechnology, with a focus on precision and scientific excellence.

Qualifications

• 1-2+ years experience with Master's degree or 3-4+ years with Bachelor's in cell biology or related.
• Prior experience in immortalized cell culture and plate-based assays.
• Hands-on experience with CAR-T therapy products.

Responsibilities

• Plan and execute ELISA, AlphaLISA, and other assays.
• Test samples for CAR-T cell therapy programs.
• Maintain good electronic lab notebook (ELN) practices.

Skills

Analytical Problem Solving

Organizational Skills

Cell Culture Experience

Education

Master’s degree in a scientific discipline

Bachelor’s degree with 3-4 years experience

Tools

ELISA

AlphaLISA

Kinexa

Biacore

MSD

Job description

Job DescriptionJob Description

Mason-Grey is hiring an R&D Scientist II that has experience with CAR-T cell therapy. Join the M-G Team and support leading research & development efforts at Johnson & Johnson in Malvern PA.

POSITION: R&D Scientist II / Analytical Development, Advanced Therapies, Functional Potency Method Development

LOCATION: Janssen, Malvern PA (100% On Site)

DURATION: Two Years

COMPENSATION:The hourly rate is a maximum range of $36.00 to $38.00. This will annualize to an estimated range of $72,000 to $76,000 based on 40 hour work weeks and 50 of 52 working weeks per year. OT is payable at 1.5X base rate and will add to the overall compensation based on actual hours worked.

JOB DESCRIPTION/EXPERIENCE:Scientist 2, Analytical Development, Advanced Therapies, Functional Potency Method Development

The Advanced Therapies, Functional Potency Method Development group is seeking an energetic, highly motivated scientist to support CAR-T cell therapies. The contactor will serve as a specialist in binding assay method development and assay validation.

Primary responsibilities:

• Plan and execute ELISA, AlphaLISA, luciferase reporter, and other plate-based assays

• Test samples across all CAR-T cell therapy programs

• Maintain healthy cultures of immortalized cell lines according to requirements

• Help keep a large inventory of reagent stocks maintained and well organized

• Maintain good electronic lab notebook (ELN) practices to ensure proper data documentation

• Demonstrate excellent communication and interpersonal skills

• The candidate is expected to work effectively in a team environment and well as contributing individually to meet project objectives and timelines.

Required:

• Master’s degree with at least 1-2+ years of experience or bachelor's degree with at least 3-4+ years’ experience in an appropriate scientific discipline (cell biology, immunology, biological science, or related field).

• Prior experience with immortalized cell culture (adherent and suspension cells)

• Prior experience with cell counting

• Prior experience running plate-based methods (e.g. ELISA, AlphaLISA, MSD, and luciferase reporter assays)

• Strong analytical problem solving, planning and organizational skills

:

• Hands-on experience with CAR-T or other cell and gene therapy products

• Experience with co-culture functional assays in immuno oncology

• Experience in analytical method development

• Experience in analytical method qualification and validation

• Experience with Kinexa and Biacore

• Experience with MSD

• Knowledge of ICH (Q2)R2 standards

Top Three Skills: Bachelor of Science, ELISA/AlphaLISA Experience, Cell Culture Experience

All candidates shall be legally authorized to work in the US and are subject to background screening, drug testing and verification of legal status in the United States using eVerify.

Company DescriptionThe Mason-Grey Corporation provides engineering solutions and services to process industry clients in energy, metals, plastics, biotech, pharmaceutical, and other key process markets. Today Mason-Grey executes projects and provides services to the Fortune 500 and mid-tier companies from coast to coast. Mason-Grey employees live and work in support of our mission from Massachusetts to California. Mason-Grey is headquartered in Atlanta, Georgia.Company DescriptionThe Mason-Grey Corporation provides engineering solutions and services to process industry clients in energy, metals, plastics, biotech, pharmaceutical, and other key process markets. Today Mason-Grey executes projects and provides services to the Fortune 500 and mid-tier companies from coast to coast. Mason-Grey employees live and work in support of our mission from Massachusetts to California. Mason-Grey is headquartered in Atlanta, Georgia.