PSC & Gene Therapy Scientist — Translational Development

Cell and Gene Therapy Catapult; Greater London; On-site; GBP 55,000 - 75,000; Full time

Job summary

Cell and Gene Therapy Catapult in London (Guy’s hospital) seeks a Scientist to advance PSC biology and cell therapy projects. You will work in multidisciplinary teams to plan and execute laboratory work, develop PSC expansion/differentiation protocols, and translate research processes toward clinical manufacturing and QC.

The role requires deep expertise in PSC biology, mammalian cell culture, and analytical characterisation, with a hands-on, collaborative approach and willingness to travel as

Qualifications

• Experience with PSC developmental biology and culture in 2D/3D systems.
• Experience with mammalian cell culture and aseptic technique.
• Experience with analytical characterisation of allogeneic cell therapies.
• Experience with molecular biology and flow cytometry methods.
• Experience evaluating new technologies to improve workflows.

Responsibilities

• Contribute to design and planning of laboratory work across multidisciplinary projects.
• Provide subject matter expertise in PSC biology.
• Apply analytics and characterisation of PSCs and cell types to sample analysis and development.
• Develop PSC expansion and differentiation processes to support projects.
• Translate research manufacturing processes to clinical manufacturing and QC protocols.
• Stay updated on PSC and cell therapy progress and publish findings internally.
• Plan and execute scientific protocols and manage data in line with policies.
• Record and communicate results in ELNs and reports; maintain high lab standards.

Skills

PSC developmental biology

Mammalian cell culture

Flow cytometry

Analytical characterisation

Automation scripting

Design of Experiments

Translational research

Education

PhD in stem cell therapy/developmental biology

Tools

Liquid handling systems

Job description

Cell and Gene Therapy Catapult in London (Guy’s hospital) seeks a Scientist to advance PSC biology and cell therapy projects. You will work in multidisciplinary teams to plan and execute laboratory work, develop PSC expansion/differentiation protocols, and translate research processes toward clinical manufacturing and QC.

The role requires deep expertise in PSC biology, mammalian cell culture, and analytical characterisation, with a hands-on, collaborative approach and willingness to travel as